Evidence map›Paper›PMID 29209126›Full record

ArticleWorld journal of gastroenterology2017

Intestinal parameters of oxidative imbalance in celiac adults with extraintestinal manifestations.

Agnieszka Piatek-Guziewicz, Agata Ptak-Belowska, Magdalena Przybylska-Felus, Pawel Pasko, Pawel Zagrodzki, Tomasz Brzozowski, Tomasz Mach, Malgorzata Zwolinska-Wcislo

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Agnieszka Piatek-GuziewiczDepartment of Gastroenterology and Hepatology, University Hospital, Cracow 31531, Poland.
Agata Ptak-BelowskaDepartment of Physiology, Jagiellonian University Medical College, Cracow 31531, Poland.
Magdalena Przybylska-FelusDepartment of Gastroenterology, Hepatology and Infectious Diseases, Jagiellonian University Medical College, Cracow 31531, Poland.
Pawel PaskoDepartment of Food Chemistry and Nutrition, Jagiellonian University Medical College, Cracow 30688, Poland.
Pawel ZagrodzkiDepartment of Food Chemistry and Nutrition, Jagiellonian University Medical College, Cracow 30688, Poland.
Tomasz BrzozowskiDepartment of Physiology, Jagiellonian University Medical College, Cracow 31531, Poland. mpbrzozo@cyf-kr.edu.pl.
Tomasz MachDepartment of Gastroenterology, Hepatology and Infectious Diseases, Jagiellonian University Medical College, Cracow 31531, Poland.
Malgorzata Zwolinska-WcisloDepartment of Gastroenterology, Hepatology and Infectious Diseases, Jagiellonian University Medical College, Cracow 31531, Poland.
Institute of Nuclear Physics, Polish Academy of Sciences · PLJagiellonian University · PLCracow University of Technology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate selected intestinal parameters of oxidative stress, and antioxidant capacity in adult celiac disease patients with extraintestinal manifestations.

methodsThe study involved 85 adult patients divided into the following subgroups: (1) patients with newly diagnosed celiac disease (CD) (

resultsThe mean plasma uric acid level in patients with active CD (newly diagnosed and nonadherent patients) and treated celiac patients was significantly higher than in controls (260.17 ± 53.65

conclusionIncreased intestinal expression of HSP-70 despite GFD indicates that GFD only partially reduced oxidative stress. CD patients exhibited an oxidative imbalance and inflammatory response despite GFD. Uric acid may act as an important antioxidant in CD.

Indexed as

Oxidative StressAdultAgedBiomarkersCase-Control StudiesCeliac DiseaseDiet, Gluten-FreeDuodenumFemaleHumansIntestinal MucosaMaleMiddle AgedRNA, MessengerUric AcidYoung AdultBiomarkersRNA, MessengerUric AcidApoptosisCeliac diseaseHeat-shock protein 70Hypoxia-inducible factorOxidative stressSuperoxide dismutaseTumor necrosis factor alphaUric acidVitamin D

Identifiers

PMID29209126
PMCPMC5703914
OpenAlexW2769304663

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.