Evidence map›Paper›PMID 29209118›Full record

ArticleWorld journal of gastroenterology2017

Chronic liver disease is universal in children with biliary atresia living with native liver.

Way Seah Lee, Sik Yong Ong, Hee Wei Foo, Shin Yee Wong, Chen Xi Kong, Ru Bin Seah, Ruey Terng Ng

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Way Seah LeeDepartment of Paediatrics, University Malaya Medical Centre, Kuala Lumpur 59100, Malaysia.
Sik Yong OngDepartment of Paediatrics, University Malaya Medical Centre, Kuala Lumpur 59100, Malaysia.
Hee Wei FooDepartment of Paediatrics, University Malaya Medical Centre, Kuala Lumpur 59100, Malaysia.
Shin Yee WongDepartment of Paediatrics, University Malaya Medical Centre, Kuala Lumpur 59100, Malaysia.
Chen Xi KongDepartment of Paediatrics, University Malaya Medical Centre, Kuala Lumpur 59100, Malaysia.
Ru Bin SeahDepartment of Paediatrics, University Malaya Medical Centre, Kuala Lumpur 59100, Malaysia.
Ruey Terng NgDepartment of Paediatrics, University Malaya Medical Centre, Kuala Lumpur 59100, Malaysia.
University of Malaya · MYUniversity Malaya Medical Centre · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo examine the medical status of children with biliary atresia (BA) surviving with native livers.

methodsIn this cross-sectional review, data collected included complications of chronic liver disease (CLD) (cholangitis in the preceding 12 mo, portal hypertension, variceal bleeding, fractures, hepatopulmonary syndrome, portopulmonary hypertension) and laboratory indices (white cell and platelet counts, total bilirubin, albumin, international normalized ratio, alanine aminotransferase, aspartate aminotransferase, γ-glutamyl transpeptidase). Ideal medical outcome was defined as absence of clinical evidence of CLD or abnormal laboratory indices.

resultsFifty-two children [females = 32, 62%; median age 7.4 years,

conclusionClinical or laboratory evidence of CLD are present in 98% of children with BA living with native livers after hepatoportoenterostomy. Portal hypertension and variceal bleeding may be seen in children younger than 5 years of age, underscoring the importance of medical surveillance for complications of BA starting at a young age.

Indexed as

AdolescentBiliary AtresiaChildChild, PreschoolCholangitisChronic DiseaseCross-Sectional StudiesEsophageal and Gastric VaricesFemaleFollow-Up StudiesFractures, BoneGastrointestinal HemorrhageHepatopulmonary SyndromeHumansHypertension, PortalLiverBiliary atresiaChronic liver diseaseMedical status

Identifiers

PMID29209118
PMCPMC5703937
OpenAlexW2768483232

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.