Evidence map›Paper›PMID 29209105›Full record

ArticleMediators of inflammation2017

Effects of NSAIDs on the Release of Calcitonin Gene-Related Peptide and Prostaglandin E

Vittorio Vellani, Giorgia Moschetti, Silvia Franchi, Chiara Giacomoni, Paola Sacerdote, Giada Amodeo

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Potential predictors for the efficacy of non-steroidal anti-inflammatory drugs in patients with migraine.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Vittorio VellaniDipartimento di Scienze Biomediche, Metaboliche e Neuroscienze, Università di Modena e Reggio Emilia, Via Campi 287, 41125 Modena, Italy.ORCID 0000-0002-3581-6654
Giorgia MoschettiDipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Via Vanvitelli 32, 20129 Milano, Italy.ORCID 0000-0001-7763-4421
Silvia FranchiDipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Via Vanvitelli 32, 20129 Milano, Italy.ORCID 0000-0002-0933-1522
Chiara GiacomoniDipartimento di Economia, Scienze e Diritto, Salita alla Rocca 44, 47890 San Marino, San Marino.ORCID 0000-0002-3444-3710
Paola SacerdoteDipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Via Vanvitelli 32, 20129 Milano, Italy.ORCID 0000-0003-4577-511X
Giada AmodeoDipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Via Vanvitelli 32, 20129 Milano, Italy.ORCID 0000-0002-4097-3195
University of Milan · ITUniversity of Modena and Reggio Emilia · ITUniversity of the Republic of San Marino · SM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently used to treat migraine, but the mechanisms of their effects in this pathology are not fully elucidated. The trigeminal ganglia and calcitonin gene-related peptide (CGRP) have been implicated in the pathophysiology of migraine. The release of CGRP and prostaglandin E

Indexed as

AnimalsAnti-Inflammatory Agents, Non-SteroidalCalcitonin Gene-Related PeptideCells, CulturedDinoprostoneMaleRatsRats, Sprague-DawleyTrigeminal GanglionAnti-Inflammatory Agents, Non-SteroidalCalcitonin Gene-Related PeptideDinoprostone

Identifiers

PMID29209105
PMCPMC5676472
OpenAlexW2766679464

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.