Evidence map›Paper›PMID 29208923›Full record

ArticleScientific reports2017

Plant-endophytes interaction influences the secondary metabolism in Echinacea purpurea (L.) Moench: an in vitro model.

Valentina Maggini, Marinella De Leo, Alessio Mengoni, Eugenia Rosaria Gallo, Elisangela Miceli, Rose Vanessa Bandeira Reidel, Sauro Biffi, Luisa Pistelli, Renato Fani, Fabio Firenzuoli and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Plant-Endophyte Cross-Talk inMicroorganisms · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Genomic, Molecular, and Phenotypic Characterization ofInternational journal of molecular sciences · 2023
    Article
  8. Article
  9. Article
  10. Endophyte-inoculated rhizomes ofFrontiers in microbiology · 2023
    Article
  11. Review
  12. Review
  13. Synergism of endophyticFrontiers in plant science · 2022
    Article
  14. Article
  15. Article
  16. Transcriptional dynamics ofFrontiers in microbiology · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Valentina MagginiDepartment of Biology, University of Florence, Via Madonna del Piano 6, 50019, Sesto Fiorentino, Italy. valentina.maggini@unifi.it.ORCID 0000-0002-4227-7214
Marinella De LeoDepartment of Pharmacy, University of Pisa, Via Bonanno 33, 56126, Pisa, Italy.
Alessio MengoniDepartment of Biology, University of Florence, Via Madonna del Piano 6, 50019, Sesto Fiorentino, Italy.ORCID 0000-0002-1265-8251
Eugenia Rosaria GalloDepartment of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 3, 50134, Florence, Italy.
Elisangela MiceliDepartment of Biology, University of Florence, Via Madonna del Piano 6, 50019, Sesto Fiorentino, Italy.
Rose Vanessa Bandeira ReidelDepartment of Pharmacy, University of Pisa, Via Bonanno 33, 56126, Pisa, Italy.
Sauro BiffiBotanical Garden Casola Valsenio, Via del Corso 6, 48010, Ravenna, Italy.
Luisa PistelliDepartment of Pharmacy, University of Pisa, Via Bonanno 33, 56126, Pisa, Italy.
Renato FaniDepartment of Biology, University of Florence, Via Madonna del Piano 6, 50019, Sesto Fiorentino, Italy.
Fabio FirenzuoliReferring Center for Phytotherapy, Tuscany Region, Careggi University Hospital, Largo Brambilla 3, 50134, Florence, Italy.
Patrizia BoganiDepartment of Biology, University of Florence, Via Madonna del Piano 6, 50019, Sesto Fiorentino, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The influence of the interaction(s) between the medicinal plant Echinacea purpurea (L.) Moench and its endophytic communities on the production of alkamides is investigated. To mimic the in vivo conditions, we have set up an infection model of axenic in vitro E. purpurea plants inoculated with a pool of bacterial strains isolated from the E. purpurea stems and leaves. Here we show different alkamide levels between control (not-inoculated) and inoculated plants, suggesting that the alkamide biosynthesis may be modulated by the bacterial infection. Then, we have analysed the branched-chain amino acids (BCCA) decarboxylase gene (GenBank Accession #LT593930; the enzymatic source for the amine moiety formation of the alkamides) expression patterns. The expression profile shows a higher expression level in the inoculated E. purpurea tissues than in the control ones. These results suggest that the plant-endophyte interaction can influence plant secondary metabolism affecting the therapeutic properties of E. purpurea.

Indexed as

Secondary MetabolismCarboxy-LyasesEchinaceaEndophytesGene Expression Regulation, PlantGerminationPlant ProteinsPolyunsaturated AlkamidesCarboxy-LyasesPlant ProteinsPolyunsaturated Alkamides

Identifiers

PMID29208923
PMCPMC5717142

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.