Evidence map›Paper›PMID 29208761›Full record

ArticleDisease models & mechanisms2018

Priming of innate antimycobacterial immunity by heat-killed

Hanna Luukinen, Milka Marjut Hammarén, Leena-Maija Vanha-Aho, Aleksandra Svorjova, Laura Kantanen, Sampsa Järvinen, Bruno Vincent Luukinen, Eric Dufour, Mika Rämet, Vesa Pekka Hytönen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Disease models & mechanisms, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Lactobacillus rhamnosus GG treatment potentiates ethanol-induced behavioral changes through modulation of intestinal epithelium in Danio rerio.International microbiology : the official journal of the Spanish Society for Microbiology · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Modeling Tuberculosis in Mycobacterium marinum Infected Adult Zebrafish.Journal of visualized experiments : JoVE · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Hanna LuukinenFaculty of Medicine and Life Sciences, FI-33014 University of Tampere, Tampere, Finland.
Milka Marjut HammarénFaculty of Medicine and Life Sciences, FI-33014 University of Tampere, Tampere, Finland milka.hammaren@uta.fi.ORCID 0000-0001-9076-8782
Leena-Maija Vanha-AhoFaculty of Medicine and Life Sciences, FI-33014 University of Tampere, Tampere, Finland.
Aleksandra SvorjovaFaculty of Medicine and Life Sciences, FI-33014 University of Tampere, Tampere, Finland.
Laura KantanenFaculty of Medicine and Life Sciences, FI-33014 University of Tampere, Tampere, Finland.
Sampsa JärvinenFaculty of Medicine and Life Sciences, FI-33014 University of Tampere, Tampere, Finland.
Bruno Vincent LuukinenFaculty of Medicine and Life Sciences, FI-33014 University of Tampere, Tampere, Finland.ORCID 0000-0003-3578-782X
Eric DufourFaculty of Medicine and Life Sciences, FI-33014 University of Tampere, Tampere, Finland.
Mika RämetFaculty of Medicine and Life Sciences, FI-33014 University of Tampere, Tampere, Finland.
Vesa Pekka HytönenFaculty of Medicine and Life Sciences, FI-33014 University of Tampere, Tampere, Finland.
Mataleena ParikkaFaculty of Medicine and Life Sciences, FI-33014 University of Tampere, Tampere, Finland.ORCID 0000-0001-5555-3815
Tampere University · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycobacterium tuberculosis remains one of the most problematic infectious agents, owing to its highly developed mechanisms to evade host immune responses combined with the increasing emergence of antibiotic resistance. Host-directed therapies aiming to optimize immune responses to improve bacterial eradication or to limit excessive inflammation are a new strategy for the treatment of tuberculosis. In this study, we have established a zebrafish-

Indexed as

Immunity, InnateSterilizationAgingAnimalsBacterial LoadBacterial ProteinsCross-PrimingDisease Models, AnimalDown-RegulationFemaleHot TemperatureLarvaListeria monocytogenesMacrophagesMaleMycobacterium marinumBacterial ProteinsNucleic AcidsZebrafish ProteinsListeria monocytogenesMycobacterial infectionMycobacterium marinumSterilizing immunityTuberculosisZebrafish

Identifiers

PMID29208761
PMCPMC5818079
OpenAlexW2773442344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.