Evidence map›Paper›PMID 29208749›Full record

ArticlemBio2017

Development of Anti-Virulence Approaches for Candidiasis via a Novel Series of Small-Molecule Inhibitors of

Jesus A Romo, Christopher G Pierce, Ashok K Chaturvedi, Anna L Lazzell, Stanton F McHardy, Stephen P Saville, Jose L Lopez-Ribot

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 105 citations in OpenAlex.

  1. Article
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  15. Imaging-based screening identifies modulators of thebioRxiv : the preprint server for biology · 2023
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  17. Frontiers in cellular and infection microbiology · 2023
    Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jesus A RomoDepartment of Biology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, Texas, USA.
Christopher G PierceDepartment of Biology, University of the Incarnate Word, San Antonio, Texas, USA.
Ashok K ChaturvediDepartment of Biology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, Texas, USA.
Anna L LazzellDepartment of Biology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, Texas, USA.
Stanton F McHardyDepartment of Chemistry and Center for Innovation in Drug Discovery, The University of Texas at San Antonio, San Antonio, Texas, USA.
Stephen P SavilleDepartment of Biology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, Texas, USA stephen.saville@utsa.edu jose.lopezribot@utsa.edu.
Jose L Lopez-RibotDepartment of Biology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, Texas, USA stephen.saville@utsa.edu jose.lopezribot@utsa.edu.
Texas Center for Infectious Disease · USThe University of Texas at San Antonio · USCenter for Innovation · USUniversity of the Incarnate Word · US

Funding

UTSA RISE Research Training ProgramR25GM060655 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI BAREA-RODRIGUEZ, EDWIN J · 2000 to 2022
$21.6M
Development of novel chemical series of Candida albicans biofilm inhibitorsR01AI119554 · NIAID · UNIVERSITY OF TEXAS SAN ANTONIO · PI LOPEZ-RIBOT, JOSE L., MCHARDY, STANTON FURST · 2015 to 2019
$1.8M
NRG1 Regulated Genes in Candida albicans PathogenicityR01AI063256 · NIAID · UNIVERSITY OF TEXAS SAN ANTONIO · PI SAVILLE, STEPHEN P · 2006 to 2009
$1.1M
Small molecule inhibitors of Candida albicans biofilm formationR21DE017294 · NIDCR · UNIVERSITY OF TEXAS SAN ANTONIO · PI LOPEZ-RIBOT, JOSE L. · 2007 to 2008
$376k
NIAID NIH HHS R01 AI063256NIAID NIH HHS R01 AI119554NIDCR NIH HHS R21 DE017294NIGMS NIH HHS R25 GM060655
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntifungal AgentsBenzamidesBiofilmsCandida albicansCandidiasisCell SurvivalDisease Models, AnimalDose-Response Relationship, DrugDrug Evaluation, PreclinicalFemaleHyphaeMiceMice, Inbred BALB CSmall Molecule LibrariesVirulenceAntifungal AgentsBenzamidesSmall Molecule LibrariesVirulence Factorsantifungal drugsanti-virulence factorCandida albicansfilamentationlarge-scale phenotypic screening

Identifiers

PMID29208749
PMCPMC5717394
OpenAlexW2774358439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.