Evidence map›Paper›PMID 29208690›Full record

Trial reportPhysiological reports2017

Aortic hemodynamics in postmenopausal women following cessation of hormone therapy.

Ronée E Harvey, Maja C Johnson, Sushant M Ranadive, Michael J Joyner, Brian D Lahr, Virginia M Miller, Jill N Barnes

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Lessons from KEEPS: the Kronos Early Estrogen Prevention Study.Climacteric : the journal of the International Menopause Society · 2021
    Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Integrative cardiovascular control in women: Regulation of blood pressure, body temperature, and cerebrovascular responsiveness.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ronée E HarveyMayo Clinic College of Medicine and Science, Mayo Clinic, Rochester, Minnesota.
Maja C JohnsonDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota.
Sushant M RanadiveDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota.
Michael J JoynerDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota.
Brian D LahrDepartment of Health Science Research, Mayo Clinic, Rochester, Minnesota.
Virginia M MillerDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota.
Jill N BarnesDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota.
Mayo Clinic · USMayo Clinic in Florida · USUniversity of Wisconsin–Madison · US

Funding

Neurovascular Control and Blood Pressure Regulation in HumansR01HL083947 · NHLBI · MAYO CLINIC ROCHESTER · PI JOYNER, MICHAEL J · 2007 to 2016
$3.6M
NHLBI NIH HHS R01 HL083947
6 · The paper itself

Abstract

Central (aortic) blood pressure and aortic pulse wave characteristics are measures of cardiovascular health, predictive of cardiovascular mortality. Previous studies have compared aortic hemodynamics in women who do and do not take menopausal hormone therapy, but characteristics of these parameters following cessation of treatment have not been defined. Therefore, the purpose of this study was to define aortic pulse wave characteristics in postmenopausal women with and without a history of menopausal hormone therapy use. Pulse wave analysis was conducted on 67 women who had participated in the randomized, double-blind, placebo-controlled Kronos Early Estrogen Prevention Study (KEEPS), 3 years subsequent to the four-year treatment period. Treatment was oral conjugated equine estrogen (0.45 mg/day;

Indexed as

Blood PressureAdministration, CutaneousAdministration, OralAortaEstradiolEstrogen Replacement TherapyEstrogensFemaleHumansMiddle AgedPostmenopauseProgesteroneProgestinsWithholding TreatmentEstradiolEstrogensProgesteroneProgestinsAugmentation indexblood pressureestrogen

Identifiers

PMID29208690
PMCPMC5727285
OpenAlexW2772812157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.