Evidence map›Paper›PMID 29208630›Full record

ArticleGenetics2018

Regulated Alternative Splicing of

Sarah K Kerwin, Joshua Shing Shun Li, Peter G Noakes, Grace Ji-Eun Shin, S Sean Millard

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Frontiers in molecular neuroscience · 2024
    Article
  2. Neural specification, targeting, and circuit formation during visual system assembly.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  3. Article
  4. Extrinsic Factors Regulating Dendritic Patterning.Frontiers in cellular neuroscience · 2020
    Review
  5. Deterministic splicing ofScience advances · 2019
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sarah K KerwinSchool of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, 4072, Australia.
Joshua Shing Shun LiSchool of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, 4072, Australia.ORCID 0000-0003-1723-0964
Peter G NoakesSchool of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, 4072, Australia.
Grace Ji-Eun ShinSchool of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, 4072, Australia.ORCID 0000-0003-0776-7856
S Sean MillardSchool of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, 4072, Australia s.millard@uq.edu.au.ORCID 0000-0001-8573-4625
University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

How the brain makes trillions of synaptic connections using a genome of only 20,000 genes is a major question in modern neuroscience. Alternative splicing is one mechanism that can increase the number of proteins produced by each gene, but its role in regulating synapse formation is poorly understood. In

Indexed as

Alternative SplicingAnimalsAnimals, Genetically ModifiedDendritesDrosophila ProteinsMutationNeural Cell Adhesion MoleculesPhotoreceptor Cells, InvertebrateProtein IsoformsSynapsesDrosophila ProteinsDscam2 protein, DrosophilaNeural Cell Adhesion MoleculesProtein IsoformsDrosophilaDscam2isoformsplicingsynapse

Identifiers

PMID29208630
PMCPMC5788533
OpenAlexW2774512259

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.