Evidence map›Paper›PMID 29208478›Full record

Trial reportJournal of pain and symptom management2018

Pilot Testing of a Brief Couple-Based Mind-Body Intervention for Patients With Metastatic Non-Small Cell Lung Cancer and Their Partners.

Kathrin Milbury, Rosalinda Engle, Anne Tsao, Zhongxing Liao, April Owens, Alejandro Chaoul, Eduardo Bruera, Lorenzo Cohen

Abstract readClinical Trial
In one paragraph

Trial report in Journal of pain and symptom management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Understanding benefit finding among patients with colorectal cancer: a longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kathrin MilburyDepartment of Palliative, Rehabilitative & Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Electronic address: kmilbury@mdanderson.org.
Rosalinda EngleDepartment of Palliative, Rehabilitative & Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Anne TsaoDepartment of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Zhongxing LiaoDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
April OwensDepartment of Palliative, Rehabilitative & Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Alejandro ChaoulDepartment of Palliative, Rehabilitative & Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Eduardo BrueraDepartment of Palliative, Rehabilitative & Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Lorenzo CohenDepartment of Palliative, Rehabilitative & Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Funding

Couple-Based Mind-Body Program for Lung Cancer Patients and their PartnersK01AT007559 · NCCIH · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MILBURY, KATHRIN · 2013 to 2017
$652k
Couple-based meditation program for patients with metastatic lung cancer and their partnersR21CA191711 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MILBURY, KATHRIN · 2016 to 2017
$383k
NCCIH NIH HHS K01 AT007559NCI NIH HHS R21 CA191711
6 · The paper itself

Abstract

contextGiven the generally incurable nature of metastatic lung cancer, patients and their spouses/partners are at risk for psychological and spiritual distress. To address this concern, we developed a couple-based mind-body (CBMB) intervention.

objectivesThis formative research aimed at examining the intervention's acceptability and initial efficacy in patients with metastatic lung cancer undergoing treatment and their spouses.

methodsIntervention content evaluation sessions and an ensuing single-arm trial were conducted. To evaluate intervention content, participants performed intervention exercises and then participated in semistructured interviews and completed written evaluations. In the single-arm trial, four intervention sessions were delivered over two weeks, focusing on cultivating mindfulness, interpersonal connection, gratitude, and purpose. Newly recruited couples completed measures of depressive symptoms, cancer distress, spiritual well-being, and sleep disturbances before and after the intervention.

resultsContent evaluations by seven dyads of patients and their partners revealed high acceptability ratings for the CBMB intervention (e.g., all participants would recommend the intervention). Consent and adherence rates (54% and 67%, respectively) were acceptable in the single-arm trial. All patients (n = 7 dyads; 67% male; mean age, 55 years) and partners (33% male; mean age, 59 years) rated the intervention as useful. Paired t-test analyses revealed large effect sizes for reduced sleep disturbances (d = 1.83) and medium effect sizes for cancer-specific distress (d = 0.61) for patients and large effect sizes for depressive symptoms (d = 0.90) for partners.

conclusionBased on these results, the CBMB intervention appears to be acceptable and subjectively useful. In addition, we observed preliminary evidence of quality of life gains in both patients and their partners.

Indexed as

Mind-Body TherapiesAgedCarcinoma, Non-Small-Cell LungDepressionFemaleHumansMaleMiddle AgedNeoplasm MetastasisPilot ProjectsQuality of LifeSexual PartnersSleep Wake DisordersSpiritualitySpousesStress, PsychologicalcouplesMetastatic non-small cell lung cancermind-body interventionquality of lifespiritual well-being

Identifiers

PMID29208478
PMCPMC6620018

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.