Evidence map›Paper›PMID 29208438›Full record

ReviewThe Lancet. Oncology2017

An integrated multidisciplinary algorithm for the management of spinal metastases: an International Spine Oncology Consortium report.

Daniel E Spratt, Whitney H Beeler, Fabio Y de Moraes, Laurence D Rhines, Joseph J Gemmete, Neeraj Chaudhary, David B Shultz, Sean R Smith, Alejandro Berlin, Max Dahele and 5 more

Abstract readComparative StudyReview
PubMed Publisher
In one paragraph

Review in The Lancet. Oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 162 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
162citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

162 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Pooled it
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  4. A critical appraisal of clinical practice guidelines on surgical treatments for spinal metastasis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Pooled it
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  10. Spinal metastasis: diagnosis, management and follow-up.The British journal of radiology · 2019
    Pooled it
  11. Trial
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  18. [Surgical management of spinal metastases].Orthopadie (Heidelberg, Germany) · 2026
    Review
  19. Surgery of the tumors of the spine.EFORT open reviews · 2026
    Article
  20. Exploring clinical and demographic determinants of time to treatment in spinal metastases: A Large-Scale cohort study of more than 1000 patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article

102 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Daniel E SprattDepartment of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA. Electronic address: sprattda@med.umich.edu.
Whitney H BeelerDepartment of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Fabio Y de MoraesDepartment of Radiation Oncology, Princess Margaret Cancer Center, University of Toronto, Toronto, ON, Canada; Department of Radiation Oncology, Hospital Sirio-Libanes, São Paulo, Brazil.
Laurence D RhinesDepartment of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Joseph J GemmeteDepartment of Radiology, University of Michigan, Ann Arbor, MI, USA.
Neeraj ChaudharyDepartment of Radiology, University of Michigan, Ann Arbor, MI, USA.
David B ShultzDepartment of Radiation Oncology, Princess Margaret Cancer Center, University of Toronto, Toronto, ON, Canada.
Sean R SmithDepartment of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, USA.
Alejandro BerlinDepartment of Radiation Oncology, Princess Margaret Cancer Center, University of Toronto, Toronto, ON, Canada.
Max DaheleDepartment of Radiation Oncology, VU University Medical Center, Amsterdam, Netherlands.
Ben J SlotmanDepartment of Radiation Oncology, VU University Medical Center, Amsterdam, Netherlands.
Kelly C YoungeDepartment of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Mark BilskyDepartment of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Paul ParkDepartment of Neurosurgery, University of Michigan, Ann Arbor, MI, USA.
Nicholas J SzerlipDepartment of Neurosurgery, University of Michigan, Ann Arbor, MI, USA.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
6 · The paper itself

Abstract

Spinal metastases are becoming increasingly common because patients with metastatic disease are living longer. The close proximity of the spinal cord to the vertebral column limits many conventional therapeutic options that can otherwise be used to treat cancer. In response to this problem, an innovative multidisciplinary approach has been developed for the management of spinal metastases, leveraging the capabilities of image-guided stereotactic radiosurgery, separation surgery, vertebroplasty, and minimally invasive local ablative approaches. In this Review, we discuss the variables that should be considered during the management of these patients and review the role of each discipline and their respective management options to provide optimal care. This work is synthesised into a practical algorithm to aid clinicians in the management of patients with spinal metastasis.

Indexed as

AlgorithmsCombined Modality TherapyCongresses as TopicDecompression, SurgicalElectromyographyFemaleHumansInterdisciplinary CommunicationInternationalityMagnetic Resonance ImagingMaleRadiosurgeryRadiotherapy, ConformalSpinal Cord CompressionSpinal NeoplasmsTomography, X-Ray Computed

Identifiers

PMID29208438

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.