Evidence map›Paper›PMID 29207980›Full record

Trial reportBMC health services research2017

Pilot randomised controlled trial of culturally adapted cognitive behavior therapy for psychosis (CaCBTp) in Pakistan.

Muhammed Omair Husain, Imran B Chaudhry, Nasir Mehmood, Raza Ur Rehman, Ajmal Kazmi, Munir Hamirani, Tayyeba Kiran, Ameer Bukhsh, Paul Bassett, Muhammad Ishrat Husain and 2 more

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC health services research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02202694 nacompletednot on this map

Feasibility Study of Culturally Adapted Cognitive Behavior Therapy for Psychosis in Pakistan

TypeinterventionalSponsorPakistan Institute of Living and LearningRan2012 to 2014Enrolled36ConditionsPsychosisArmsCulturally Adapted Cognitive behavior therapy
NCT06301347 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Integrated Parenting Intervention for Parents With Schizophrenia: A Feasibility Randomized Controlled Trial in Pakistan

TypeinterventionalSponsorPakistan Institute of Living and LearningRan2024 to 2025Enrolled90ConditionsPsychosisArmsLearning through Play Plus
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 26 citations in OpenAlex.

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  10. Add-on Sodium Benzoate andSchizophrenia bulletin open · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Muhammed Omair HusainFaculty of Medical and Human Sciences, University of Manchester, Room G.907, Stopford Building, Oxford Road, Manchester, M13 9PT, UK. m0301729@doctors.org.uk.ORCID http://orcid.org/0000-0001-5712-7094
Imran B ChaudhryFaculty of Medical and Human Sciences, University of Manchester, Room G.907, Stopford Building, Oxford Road, Manchester, M13 9PT, UK.
Nasir MehmoodPakistan Institute of Learning and Living, Karachi, Pakistan.
Raza Ur RehmanDow University of Health Sciences, Karachi, Pakistan.
Ajmal KazmiPakistan Institute of Learning and Living, Karachi, Pakistan.
Munir HamiraniAbbasi Shaheed Hospital, Karachi, Pakistan.
Tayyeba KiranPakistan Institute of Learning and Living, Karachi, Pakistan.
Ameer BukhshPakistan Institute of Learning and Living, Karachi, Pakistan.
Paul BassettStatsconsultancy Ltd, Amersham, UK.
Muhammad Ishrat HusainCamden and Islington NHS Foundation Trust, London, UK.
Farooq NaeemQueens' University, Kingston, ON, Canada.
Nusrat HusainFaculty of Medical and Human Sciences, University of Manchester, Room G.907, Stopford Building, Oxford Road, Manchester, M13 9PT, UK.
Pakistan Institute of Learning and Living · PKUniversity of Manchester · GBAbbasi Shaheed Hospital · PKDow University of Health Sciences · PKQueen's University · CA

Funding

International Health Links Funding Scheme IHLFS/PILL/239/DUHS-11Pakistan Institute of Living and Learning IHLFS/PILL/239/DUHS-11
6 · The paper itself

Abstract

backgroundEvidence for efficacy of cognitive-behavioural therapy (CBT) in treatment of schizophrenia is growing. CBT is effective and cost efficient in treating positive and negative symptoms. To effectively meet the needs of diverse cultural groups, CBT needs to be adapted to the linguistic, cultural and socioeconomic context. We aimed to assess the feasibility, efficacy and acceptability of a culturally adapted CBT for treatment of psychosis (CaCBTp) in a low-income country.

methodsRater-blind, randomised, controlled trial of the use of standard duration CBT in patients with psychosis from a low-income country. Participants with a ICD-10 diagnosis of psychosis were assessed using Positive and Negative Syndrome Scale for Schizophrenia (PANSS), Psychotic Symptom Rating Scales (PSYRATS), and the Schedule for Assessment of Insight (SAI) (baseline, 3 months and 6 months). They were randomized into the intervention group (n = 18) and Treatment As Usual (TAU) group (n = 18). The intervention group received 12 weekly sessions of CaCBTp.

resultsThe CaCBTp group had significantly lower scores on PANSS Positive (p = 0.02), PANSS Negative (p = 0.045), PANSS General Psychopathology (p = 0.008) and Total PANSS (p = 0.05) when compared to TAU at three months. They also had low scores on Delusion Severity Total (p = 0.02) and Hallucination Severity Total (p = 0.04) of PSYRATS, as well as higher scores on SAI (p = 0.01) at the same time point. At six months only the improvement in PANSS positive scores (p = 0.045) met statistical significance..

conclusionsIt is feasible to offer CaCBTp as an adjunct to TAU in patients with psychosis, presenting to services in a lower middle-income country.

trial registrationClinicaltrials.gov identifier NCT02202694 (Retrospectively registered).

Indexed as

Cognitive Behavioral TherapyCulturally Competent CareAdultDeveloping CountriesFemaleHallucinationsHumansMalePakistanPilot ProjectsPsychiatric Status Rating ScalesPsychotic DisordersSchizophreniaSocioeconomic FactorsCognitive behavioural therapyCulturePakistanPsychosisSchizophrenia

Identifiers

PMID29207980
PMCPMC5718081
OpenAlexW2775398832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.