Evidence map›Paper›PMID 29207972›Full record

ArticleBMC surgery2017

Disparities in the regional, hospital and individual levels of antibiotic use in gallstone surgery in Sweden.

Gona Jaafar, Bahman Darkahi, Lars Lindhagen, Gunnar Persson, Gabriel Sandblom

Abstract read
In one paragraph

Article in BMC surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gona JaafarDepartment of Clinical Sciences, Intervention and Technology (CLINTEC), Karolinska Institutet, Center for Digestive Diseases, Karolinska University Hospital, -141 86, Stockholm, SE, Sweden. gona.jaafar@karolinska.se.
Bahman DarkahiDepartment of Surgery, Enköping Hospital, Kungsgatan 71, 74538, Enköping, Sweden.
Lars LindhagenUppsala Clinical Research Centre, Dag Hammarskjölds väg 14B, 75237, Uppsala, Sweden.
Gunnar PerssonDepartment of Surgery, Växjö Hospital, Strandvägen 8, 35185, Växjö, Sweden.
Gabriel SandblomDepartment of Clinical Sciences, Intervention and Technology (CLINTEC), Karolinska Institutet, Center for Digestive Diseases, Karolinska University Hospital, -141 86, Stockholm, SE, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntimicrobial resistance may be promoted by divergent routines and lack of conformity in antibiotic treatment, especially regarding the practice of antibiotic prophylaxis. The aim of the present study was to assess differences in gallstone surgery regarding antibiotic use in Sweden.

methodsThe study was based on data from the Swedish Register for Gallstone Surgery and ERCP (GallRiks) 2005-2015. Funnel plots were used to test impact of grouping factors, including, hospital and surgeon and to identify units that deviated from the rest of the population.

resultsAfter adjusting for cofounders including age, gender, ASA classification, indication for surgery, operation time, gallbladder perforation and emergency status, there were 0/21 (0%) at the regional level, 18/76 (24%) at the hospital level and 128/1038 (12%) at the surgeon level outside the 99.9% confidence interval (CI). The estimated median odds ratios were 1.13 (95% CI 1.00-1.31) at the regional level, 1.93 (95% CI 1.70-2.19) at the hospital level and 2.38 (95% CI 2.26-2.50) at the surgeon level.

conclusionThere are significant differences between hospitals and surgeons, but little or no differences between regions. These deviations confirm the lack of standardization in regards to prescription of antibiotic prophylaxis and the need more uniform routines regarding antibiotic usage. Randomized controlled trials and large population-based studies are necessary to assess assessing the effectiveness and safety of antibiotic prophylaxis in gallstone surgery.

Indexed as

CholecystectomyAdultAgedAged, 80 and overAnti-Bacterial AgentsAntibiotic ProphylaxisFemaleGallstonesHealthcare DisparitiesHumansMaleMiddle AgedOdds RatioPerioperative CarePractice Patterns, Physicians'RegistriesAnti-Bacterial AgentsCholecystectomyCholecystitisManagement programmeProphylactic antibiotic

Identifiers

PMID29207972
PMCPMC5717817

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.