Evidence map›Paper›PMID 29207698›Full record

ArticleJournal of clinical and diagnostic research : JCDR2017

Protective effects of Ethanolic Extract of

Pallavi Shantkumar Kanthe, Bheemshetty S Patil, Shrilaxmi C Bagali, R Chandramouli Reddy, Manjunatha R Aithala, Kusal K Das

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

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  4. Mineral and Phenolic Composition ofOxidative medicine and cellular longevity · 2022
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  5. Article
  6. Cardiovascular & hematological agents in medicinal chemistry · 2019
    Article
  7. StandardizedInternational journal of molecular sciences · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Pallavi Shantkumar KanthePhD Scholar, Department of Laboratory of Vascular Physiology and Medicine, Department of Physiology, BLDE University Shri B. M. Patil Medical College, Hospital and Research Centre, Vijayapura, Karnataka, India.
Bheemshetty S PatilLecturer, Department of Anatomy, BLDE University Shri B. M. Patil Medical College, Hospital and Research Centre, Vijayapura, Karnataka, India.
Shrilaxmi C BagaliAssistant Professor, Department of Laboratory of Vascular Physiology and Medicine, Department of Physiology, BLDE University Shri B. M. Patil Medical College, Hospital and Research Centre, Vijayapura, Karnataka, India.
R Chandramouli ReddyJunior Research Scientist, Department of Laboratory of Vascular Physiology and Medicine, Department of Physiology, BLDE University Shri B. M. Patil Medical College, Hospital and Research Centre, Vijayapura, Karnataka, India.
Manjunatha R AithalaProfessor and Head, Department of Physiology, BLDE University Shri B. M. Patil Medical College, Hospital and Research Centre, Vijayapura, Karnataka, India.
Kusal K DasProfessor, Department of Laboratory of Vascular Physiology and Medicine, Department of Physiology, BLDE University Shri B. M. Patil Medical College, Hospital and Research Centre, Vijayapura, Karnataka, India.
Shri BM Patil Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDietary high fat alters lipid profile and possibly induce sympatho-vagal imbalance.

aimTo assess Ethanolic extract of MATERIALS AND

methodsEEO was prepared and phytochemical analysis was done. Rats were divided into five groups, having six rats in each group as following; Group I-control (20% fat); Group II (+ EEO 100 mg/kg body wt); Group III (fed with high fat diet; 30% fat); Group IV (fed with high fat diet; 30% fat + EEO 100 mg/kg body wt) and Group V (fed with high fat diet; 30% fat + atorvastatin 4 mg/kg body wt). The treatments were continued for 21 days. Gravimetric parameters and electrophysiological parameters {Heart Rate (HR), sympatho-vagal balance} were recorded and lipid profiles of all the groups were measured. ANOVA, correlation and multiple regressions were done for analysis of data.

resultsSignificant alteration in serum lipid profile was observed in rats fed with high dietary fat but supplementation of EEO was found to be reversible. Electrophysiological evaluation revealed altered HR and sympatho-vagal balance in high dietary fat fed rats (Group III) which indicate cardiac autonomic malfunctions which were found to be improved in

conclusionObservations from the study indicate a beneficial role of ethanolic extract of

Indexed as

Atorvastatin high fat dietLipid profileSympatho-vagal balance

Identifiers

PMID29207698
PMCPMC5713720
OpenAlexW2761404773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.