ArticleOncotarget2017
Nitidine chloride acts as an apoptosis inducer in human oral cancer cells and a nude mouse xenograft model via inhibition of STAT3.
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Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 32 citations in OpenAlex.
- Article
- Natural STAT3 Inhibitors for Cancer Treatment: A Comprehensive Literature Review.Recent patents on anti-cancer drug discovery · 2024Review
- Review
- The multifaceted role of STAT3 pathway and its implication as a potential therapeutic target in oral cancer.Archives of pharmacal research · 2022Review
- Silymarin inhibits proliferation of human breast cancer cells via regulation of the MAPK signaling pathway and induction of apoptosis.Oncology letters · 2021Article
- Update and New Insights on Future Cancer Drug Candidates From Plant-Based Alkaloids.Frontiers in pharmacology · 2021Review
- The inhibitory effect of TU-100 on hepatic stellate cell activation in the tumor microenvironment.Oncotarget · 2020Article
- Targeting X chromosome-linked inhibitor of apoptosis protein in mucoepidermoid carcinoma of the head and neck: A novel therapeutic strategy using nitidine chloride.Journal of molecular medicine (Berlin, Germany) · 2020Article
- Targeting STAT3 in Cancer Immunotherapy.Molecular cancer · 2020Review
- Nitidine chloride inhibits the appearance of cancer stem-like properties and regulates potential the mitochondrial membrane alterations of colon cancer cells.Annals of translational medicine · 2020Article
- Cryptotanshinone chemosensitivity potentiation by TW-37 in human oral cancer cell lines by targeting STAT3-Mcl-1 signaling.Cancer cell international · 2020Article
- Antitumor functions and mechanisms of nitidine chloride in human cancers.Journal of Cancer · 2020Review
- A new insight into the apoptotic effect of nitidine chloride targeting Checkpoint kinase 2 in human cervical cancerJournal of clinical biochemistry and nutrition · 2019Article
- Natural Products and Synthetic Analogs as a Source of Antitumor Drugs.Biomolecules · 2019Review
- Pseudolaric Acid B Induces Growth Inhibition and Caspase-Dependent Apoptosis on Head and Neck Cancer Cell lines through Death Receptor 5.Molecules (Basel, Switzerland) · 2019Article
- High throughput circRNA sequencing analysis reveals novel insights into the mechanism of nitidine chloride against hepatocellular carcinoma.Cell death & disease · 2019Article
- Contribution of p38 MAPK Pathway to Norcantharidin-Induced Programmed Cell Death in Human Oral Squamous Cell Carcinoma.International journal of molecular sciences · 2019Article
- Gene profiling of HepG2 cells following nitidine chloride treatment: An investigation with microarray and Connectivity Mapping.Oncology reports · 2019Article
- 5-Hydroxy-4'-Nitro-7-Propionyloxy-Genistein Inhibited Invasion and Metastasis via Inactivating Wnt/b-Catenin Signal Pathway in Human Endometrial Carcinoma Ji Endometrial Cells.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Nitidine Chloride Is a Potential Alternative Therapy for Glioma Through Inducing Endoplasmic Reticulum Stress and Alleviating Epithelial-Mesenchymal Transition.Integrative cancer therapiesArticle
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 1 country.
Lee-Han KimDepartment of Oral Pathology, School of Dentistry, Institute of Biodegradable Material, Institute of Oral Bioscience, Chonbuk National University, Jeonju, 54896, Republic of Korea.
Sachita KhadkaDepartment of Oral Pathology, School of Dentistry, Institute of Biodegradable Material, Institute of Oral Bioscience, Chonbuk National University, Jeonju, 54896, Republic of Korea.
Ji-Ae ShinDepartment of Oral Pathology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 03080, Republic of Korea.
Ji-Youn JungDepartment of Companion and Laboratory Animal Science, Kongju National University, Yesan, 32439, Republic of Korea.
Mi-Heon RyuDepartment of Oral Pathology, School of Dentistry, Yangsan Campus of Pusan National University, Yangsan, 50612, Republic of Korea.
Hyun-Ju YuDepartment of Oral Pathology, School of Dentistry, Institute of Biodegradable Material, Institute of Oral Bioscience, Chonbuk National University, Jeonju, 54896, Republic of Korea.
Hae Nim LeeDepartment of Companion and Laboratory Animal Science, Kongju National University, Yesan, 32439, Republic of Korea.
Boonsil JangDepartment of Oral Pathology, School of Dentistry, Institute of Biodegradable Material, Institute of Oral Bioscience, Chonbuk National University, Jeonju, 54896, Republic of Korea.
In-Hyoung YangDepartment of Oral Pathology, School of Dentistry, Institute of Biodegradable Material, Institute of Oral Bioscience, Chonbuk National University, Jeonju, 54896, Republic of Korea.
Dong-Hoon WonDepartment of Oral Pathology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 03080, Republic of Korea.
Hye-Jeong KwonDepartment of Oral Pathology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 03080, Republic of Korea.
Joseph H JeongDepartment of Developmental Biology and Genomics, College of Veterinary Medicine, Seoul National University and Korea Mouse Phenotyping Center, Seoul, 08826, Republic of Korea.
Seong Doo HongDepartment of Oral Pathology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 03080, Republic of Korea.
Nam-Pyo ChoDepartment of Oral Pathology, School of Dentistry, Institute of Biodegradable Material, Institute of Oral Bioscience, Chonbuk National University, Jeonju, 54896, Republic of Korea.
Sung-Dae ChoDepartment of Oral Pathology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 03080, Republic of Korea.
Jeonbuk National University · KRSeoul National University · KRKongju National University · KRPusan National University Yangsan Hospital · KR
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nitidine chloride (NC) is a natural alkaloid compound derived from the plant
Indexed as
apoptosisnitidine chlorideoral cancerSTAT3
Identifiers
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.