Evidence map›Paper›PMID 29207613›Full record

ArticleOncotarget2017

Changes in renal function indices in cirrhotic chronic hepatitis C patients treated with sofosbuvir-containing regimens.

Jianhong Chen, Xiaxia Zhang, Hao Luo, Chihong Wu, Min Yu, Dan Liu, Hongli Xi, Yihang Zhou, Yaoyu An, Xiaoyuan Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jianhong ChenDepartment of Infectious Disease, Peking University First Hospital, Beijing 100034, China.
Xiaxia ZhangDepartment of Infectious Disease, Peking University First Hospital, Beijing 100034, China.
Hao LuoDepartment of Infectious Disease, Peking University First Hospital, Beijing 100034, China.
Chihong WuDepartment of Infectious Disease, Peking University First Hospital, Beijing 100034, China.
Min YuDepartment of Infectious Disease, Peking University First Hospital, Beijing 100034, China.
Dan LiuDepartment of Infectious Disease, Peking University First Hospital, Beijing 100034, China.
Hongli XiDepartment of Infectious Disease, Peking University First Hospital, Beijing 100034, China.
Yihang ZhouDepartment of Infectious Disease, Peking University First Hospital, Beijing 100034, China.
Yaoyu AnDepartment of Infectious Disease, Peking University First Hospital, Beijing 100034, China.
Xiaoyuan XuDepartment of Infectious Disease, Peking University First Hospital, Beijing 100034, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to explore changes in hepatic and renal function indices in chronic hepatitis C (CHC) patients treated with direct-acting antivirals (DAAs). Forty-three CHC patients treated with sofosbuvir (SOF)-containing regimens were enrolled. At the end of treatment, the estimated glomerular filtration rate (eGFR) level was significantly decreased and the serum creatinine (Scr) and uric acid (UA) levels were significantly increased compared with baseline levels (eGFR: 86.7 ± 20.4 vs 80.5 ± 21.3,

Indexed as

chronic hepatitis Cdirectly acting antiviralsnephrotoxicitysofosbuvir

Identifiers

PMID29207613
PMCPMC5710894

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.