Evidence map›Paper›PMID 29207548›Full record

SynthesisInternational journal of molecular sciences2017

The Role of Omega-3 Fatty Acids in Developmental Psychopathology: A Systematic Review on Early Psychosis, Autism, and ADHD.

Carlo Agostoni, Maria Nobile, Valentina Ciappolino, Giuseppe Delvecchio, Alessandra Tesei, Stefano Turolo, Alessandro Crippa, Alessandra Mazzocchi, Carlo A Altamura, Paolo Brambilla

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 8 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 8 syntheses or guidelines pooled it, 125 citations in OpenAlex.

  1. Nutraceuticals in Psychiatric Disorders: A Systematic Review.International journal of molecular sciences · 2024
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  6. Effects of Omega 3 Fatty Acids on Main Dimensions of Psychopathology.International journal of molecular sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Carlo AgostoniPediatric Intermediate Care Unit, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ospedale Cà Granda-Ospedale Maggiore Policlinico, University of Milan, 20122 Milan, Italy. carlo.agostoni@unimi.it.
Maria NobileChild Psychopathology Unit, Scientific Institute, IRCCS Eugenio Medea, via Don Luigi Monza 20, Bosisio Parini, 23842 Lecco, Italy. maria.nobile@bp.lnf.it.
Valentina CiappolinoDepartment of Neurosciences and Mental Health, Fondazione IRCCS Ospedale Cà Granda-Ospedale Maggiore Policlinico, University of Milan, 20122 Milan, Italy. valentina.ciappolino@policlinico.mi.it.
Giuseppe DelvecchioDepartment of Pathophysiology and Transplantation, Fondazione IRCCS Ospedale Cà Granda-Ospedale Maggiore Policlinico, University of Milan, 20122 Milan, Italy. g.delvecchio@hotmail.it.
Alessandra TeseiChild Psychopathology Unit, Scientific Institute, IRCCS Eugenio Medea, via Don Luigi Monza 20, Bosisio Parini, 23842 Lecco, Italy. alessandra.tesei@bp.lnf.it.
Stefano TuroloPediatric Nephrology & Dialysis, Milano Fondazione IRCCS Cà Grande Ospedale Maggiore Policlinico, University of Milan, 20122 Milan, Italy. stefano.turolo@gmail.com.
Alessandro CrippaChild Psychopathology Unit, Scientific Institute, IRCCS Eugenio Medea, via Don Luigi Monza 20, Bosisio Parini, 23842 Lecco, Italy. alessandro.crippa@bp.lnf.it.
Alessandra MazzocchiPediatric Intermediate Care Unit, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ospedale Cà Granda-Ospedale Maggiore Policlinico, University of Milan, 20122 Milan, Italy. alessandra.mazzocchi@unimi.it.
Carlo A AltamuraDepartment of Neurosciences and Mental Health, Fondazione IRCCS Ospedale Cà Granda-Ospedale Maggiore Policlinico, University of Milan, 20122 Milan, Italy. carlo.altamura@unimi.it.
Paolo BrambillaDepartment of Neurosciences and Mental Health, Fondazione IRCCS Ospedale Cà Granda-Ospedale Maggiore Policlinico, University of Milan, 20122 Milan, Italy. paolo.brambilla1@unimi.it.
University of Milan · ITIRCCS Eugenio Medea · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this systematic review, we will consider and debate studies that have explored the effects of ω-3 polyunsaturated fatty acids (PUFAs) in three major, and somehow related, developmental psychiatric disorders: Autism, Attention Deficit and Hyperactivity disorder and Psychosis. The impact of ω-3 PUFAs on clinical symptoms and, if possible, brain trajectory in children and adolescents suffering from these illnesses will be reviewed and discussed, considering the biological plausibility of the effects of omega-3 fatty acids, together with their potential perspectives in the field. Heterogeneity in study designs will be discussed in the light of differences in results and interpretation of studies carried out so far.

Indexed as

Attention Deficit Disorder with HyperactivityAutistic DisorderDocosahexaenoic AcidsEicosapentaenoic AcidFatty Acids, Omega-3HumansPsychotic DisordersDocosahexaenoic AcidsEicosapentaenoic AcidFatty Acids, Omega-3attention deficit hyperactivity disorder (ADHD)autismdocosahexaenoic acid (DHA)eicosapentaenoic acid (EPA)first psychotic episodeneurodevelopmentomega-3PUFAsultra-high risk for psychosis

Identifiers

PMID29207548
PMCPMC5751211
OpenAlexW2775652281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.