ReviewSensors (Basel, Switzerland)2017
Construction and Potential Applications of Biosensors for Proteins in Clinical Laboratory Diagnosis.
Review in Sensors (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Immunosensors for Autoimmune-Disease-Related Biomarkers: A Literature Review.Sensors (Basel, Switzerland) · 2023Review
- Rapid detection of SARS-CoV-2 antibodies using electrochemical impedance-based detector.Biosensors & bioelectronics · 2021Article
- Biosensing based on field-effect transistors (FET): Recent progress and challenges.Trends in analytical chemistry : TRAC · 2020Review
- A CMOS Low Pass Filter for SoC Lock-in-Based Measurement Devices.Sensors (Basel, Switzerland) · 2019Article
- Impact of Molybdenum Compounds as Anticancer Agents.Bioinorganic chemistry and applications · 2019Review
- A 0.18 μm CMOS LDO Regulator for an On-Chip Sensor Array Impedance Measurement System.Sensors (Basel, Switzerland) · 2018Article
- Industry 4.0 Technologies for the Manufacturing and Distribution of COVID-19 Vaccines.Journal of primary care & community healthArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
Biosensors for proteins have shown attractive advantages compared to traditional techniques in clinical laboratory diagnosis. In virtue of modern fabrication modes and detection techniques, various immunosensing platforms have been reported on basis of the specific recognition between antigen-antibody pairs. In addition to profit from the development of nanotechnology and molecular biology, diverse fabrication and signal amplification strategies have been designed for detection of protein antigens, which has led to great achievements in fast quantitative and simultaneous testing with extremely high sensitivity and specificity. Besides antigens, determination of antibodies also possesses great significance for clinical laboratory diagnosis. In this review, we will categorize recent immunosensors for proteins by different detection techniques. The basic conception of detection techniques, sensing mechanisms, and the relevant signal amplification strategies are introduced. Since antibodies and antigens have an equal position to each other in immunosensing, all biosensing strategies for antigens can be extended to antibodies under appropriate optimizations. Biosensors for antibodies are summarized, focusing on potential applications in clinical laboratory diagnosis, such as a series of biomarkers for infectious diseases and autoimmune diseases, and an evaluation of vaccine immunity. The excellent performances of these biosensors provide a prospective space for future antibody-detection-based disease serodiagnosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.