A Diastereoselective Synthesis of Dispiro[oxindole-cyclohexanone]pyrrolidines by 1,3-Dipolar Cycloaddition.

Alexander Anis'kov, Irina Klochkova, Roman Tumskiy, Alevtina Yegorova

Open access · goldAbstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.4field-weighted citation impact, top 42% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

Dialkylation of Indoles with Trichloroacetimidates to Access 3,3-Disubstituted Indolenines.Molecules (Basel, Switzerland) · 2019
Article

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alexander Anis'kovInstitute of Chemistry, Chernyshevsky Saratov State University, 83 Astrakhanskaya Street, Saratov 410012, Russia. aniskovalvis@gmail.com.ORCID 0000-0002-6459-1511

Irina KlochkovaInstitute of Chemistry, Chernyshevsky Saratov State University, 83 Astrakhanskaya Street, Saratov 410012, Russia. v-klochkov1@yandex.ru.

Roman TumskiyInstitute of Chemistry, Chernyshevsky Saratov State University, 83 Astrakhanskaya Street, Saratov 410012, Russia. roma_ronaldinho@rambler.ru.

Alevtina YegorovaInstitute of Chemistry, Chernyshevsky Saratov State University, 83 Astrakhanskaya Street, Saratov 410012, Russia. yegorovaay@gmail.com.

Saratov State University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For the first time, arylmethylidene cyclohexanones that are non-symmetrical due to the presence of peripheral substituents were studied in 1,3-dipolar cycloaddition reactions. It is shown that the interaction with the azomethine ylide generated from sarcosine proceeds regio- and diastereoselectively, with the participation of two non-equivalent parts of the dipolarophile. Also for the first time, β-amino ketones (Mannich bases) were used as dipolarophile equivalents of unsaturated ketones. It was found that cycloaddition occurs diastereoselectively at the generated center.

Indexed as

Cycloaddition ReactionCyclohexanonesIndolesKetonesOxindolesPyrrolidinesStereoisomerism2-oxindolecyclohexanoneCyclohexanonesIndolesKetonesOxindolesPyrrolidines1,3-dipolar cycloadditionazomethine ylidessarcosinespiro[indoline-3,2′-pyrrolidin]-2-oneunsaturated ketones

Identifiers

PMID29207519

DOI10.3390/molecules22122134

PMCPMC6149807

OpenAlexW2775197325

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.