ArticlePloS one2017
Predictors of mercury, lead, cadmium and antimony status in Norwegian never-pregnant women of fertile age.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 36 citations in OpenAlex.
- Environmental lead exposure and clinical infectious respiratory disease in a sample of urban and disadvantaged children.Journal of exposure science & environmental epidemiology · 2026Article
- Environmental and genetic predictors of whole blood mercury and selenium concentrations in pregnant women in a UK birth cohort.Environmental advances · 2024Article
- Article
- Dietary behaviors and attitudes among Norwegian medical students.BMC medical education · 2023Article
- Metal Exposures in Residents Living Near an Urban Oil Drilling Site in Los Angeles, California.Environmental science & technology · 2022Article
- Comprehensive Review Regarding Mercury Poisoning and Its Complex Involvement in Alzheimer's Disease.International journal of molecular sciences · 2022Review
- Associations of exposure to cadmium, antimony, lead and their mixture with gestational thyroid homeostasis.Environmental pollution (Barking, Essex : 1987) · 2021Article
- Prenatal metal mixtures and sex-specific infant negative affectivity.Environmental epidemiology (Philadelphia, Pa.) · 2021Article
- Perfluoroalkyl substances (PFASs) and mercury in never-pregnant women of fertile age: association with fish consumption and unfavorable lipid profile.BMJ nutrition, prevention & health · 2020Article
- Blood Cd levels and carotid intima-media thickness in young adults living in Padang, Indonesia.BMC research notes · 2020Article
- Joint Toxicity of a Multi-Heavy Metal Mixture and Chemoprevention in Sprague Dawley Rats.International journal of environmental research and public health · 2020Article
- Blood mercury, lead, cadmium, manganese and selenium levels in pregnant women and their determinants: the Japan Environment and Children's Study (JECS).Journal of exposure science & environmental epidemiology · 2019Article
- Determinants of Erythrocyte Lead Levels in 454 Adults in Florence, Italy.International journal of environmental research and public health · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe toxic trace elements mercury (Hg), lead (Pb), cadmium (Cd) and antimony (Sb) are transferred over the placenta to the fetus and secreted into the breastmilk. All four elements bioaccumulate in the body and as maternal age at delivery is increasing in industrialized countries, the burden of toxic trace elements in never-pregnant women of fertile age is of concern.
methodsHealthy, never-pregnant women aged 18 to 40 years (n = 158) were recruited between June 2012 and March 2015 in Bergen, Norway. Clinical data were collected and non-fasting venous blood samples were analyzed for whole blood Hg, Pb and Cd and serum Sb by ICP-MS and related to diet and life style factors.
resultsIn a multiple linear regression model, increasing age was associated with higher levels of Hg and Sb, but diet and life style factors were more important predictors. Median whole blood Hg was increased by a factor of 70 in women who had fish for dinner ≥1/week, compared to women who rarely or never ate fish (p<0.001). Alcohol intake was the strongest predictor for whole blood Pb, while use of tobacco was the strongest predictor for whole blood Cd. Being a vegetarian was associated with lower levels of both Hg and Sb.
conclusionsAs toxic trace elements tend to bioaccumulate in the body, increasing maternal age at delivery may represent a threat to the next generation. In a group of healthy Norwegian never-pregnant women, age contributed to Hg and Sb levels, but diet and life style factors were stronger determinants of whole blood Hg, Pb, Cd and serum Sb levels. Continuous public actions are needed to reduce modifiable and preventable sources of potentially deleterious toxins to minimize the exposure in children and fertile women.
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