ArticleeLife2017
The Human Cell Atlas.
Abstract read
In one paragraph
Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,439 papers.
0numbers the graph read from it
0cells of the map it votes in
1,439citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1,439 citing papers in PubMed.
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- Standardizing Cell Ontology terms for cross-study integration in the female reproductive tract.Science advances · 2026Review
- Decoding epithelial-mesenchymal transitions with multi-omics.Nature reviews. Genetics · 2026Review
- ArchMap is a web-based platform for reference-based analysis of single-cell datasets.Nature genetics · 2026Article
- CytoVI: deep generative modeling of antibody-based single cell data.Nature methods · 2026Article
- 3D multi-omics tumour atlases: from technology to biology and clinical translation.Nature reviews. Cancer · 2026Review
- A graph-attentive GAN for rare-cell-aware single-cell RNA-seq data generation.PLoS computational biology · 2026Article
- Article
- Single-nucleus atlas of cell-type specific genetic regulation in the human brain.Nature genetics · 2026Article
- Ten years, tens of millions of cells.Nature biotechnology · 2026Article
- Hyperacute Interleukin-1β Production and Neutrophil Extracellular Trap Formation in the Cerebral Circulation of Stroke Patients with Large Vessel Occlusion.Annals of neurology · 2026Article
- Single-Nucleus Multi-Omic Atlas Maps Regulatory Architecture and Non-Coding Variant Effects across Adult Human Tissues.bioRxiv : the preprint server for biology · 2026Article
- celltypeEnrich: a consensus-based scRNA-seq cluster annotation tool.bioRxiv : the preprint server for biology · 2026Article
- Review
- CRISPR-Enabled functional genomics in hPSCs-derived neural models for autism spectrum disorder.Metabolic brain disease · 2026Review
- What-if effects: A tale of entangled covariates.Patterns (New York, N.Y.) · 2026Article
- Advancing the Deciphering of Host-Microbe Crosstalk with Spatial Omics: A Mini-Review.Current microbiology · 2026Review
- The PhageExpressionAtlas reveals shared and unique transcriptional patterns across phage-host interactions.NAR genomics and bioinformatics · 2026Article
- From cell atlases to mechanisms: bridging scRNA-seq discovery with in vivo genetics.The EMBO journal · 2026Article
1,379 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
62 authors.
Aviv RegevBroad Institute of MIT and Harvard, Cambridge, United States.ORCID 0000-0003-3293-3158
Sarah A TeichmannWellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Eric S LanderBroad Institute of MIT and Harvard, Cambridge, United States.
Ido AmitDepartment of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Christophe BenoistDivision of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, United States.
Ewan BirneyEMBL-European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Bernd BodenmillerEMBL-European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Peter CampbellWellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Piero CarninciCavendish Laboratory, Department of Physics, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0001-7202-7243
Menna ClatworthyMolecular Immunity Unit, Department of Medicine, MRC Laboratory of Molecular Biology, University of Cambridge, Cambridge, United Kingdom.
Hans CleversHubrecht Institute, Princess Maxima Center for Pediatric Oncology and University Medical Center Utrecht, Utrecht, The Netherlands.
Bart DeplanckeInstitute of Bioengineering, School of Life Sciences, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland.ORCID 0000-0001-9935-843X
Ian DunhamEMBL-European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
James EberwineDepartment of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States.
Roland EilsDivision of Theoretical Bioinformatics (B080), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Wolfgang EnardDepartment of Biology II, Ludwig Maximilian University Munich, Martinsried, Germany.ORCID 0000-0002-4056-0550
Andrew FarmerTakara Bio United States, Inc., Mountain View, United States.
Lars FuggerOxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, and MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.
Berthold GöttgensDepartment of Haematology, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0001-6302-5705
Nir HacohenBroad Institute of MIT and Harvard, Cambridge, United States.
Muzlifah HaniffaInstitute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0002-3927-2084
Martin HembergWellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Seung KimDepartments of Developmental Biology and of Medicine, Stanford University School of Medicine, Stanford, United States.
Paul KlenermanPeter Medawar Building for Pathogen Research and the Translational Gastroenterology Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.
Arnold KriegsteinEli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, United States.
Ed LeinAllen Institute for Brain Science, Seattle, United States.ORCID 0000-0001-9012-6552
Sten LinnarssonLaboratory for Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Emma LundbergScience for Life Laboratory, School of Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden.
Joakim LundebergScience for Life Laboratory, Department of Gene Technology, KTH Royal Institute of Technology, Stockholm, Sweden.
Partha MajumderNational Institute of Biomedical Genomics, Kalyani, India.
John C MarioniWellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Miriam MeradPrecision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, United States.
Musa MhlangaDivision of Chemical, Systems & Synthetic Biology, Institute for Infectious Disease & Molecular Medicine (IDM), Department of Integrative Biomedical Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Martijn NawijnDepartment of Pathology and Medical Biology, GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Mihai NeteaDepartment of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Garry NolanDepartment of Microbiology and Immunology, Stanford University, Stanford, United States.
Dana Pe'erComputational and Systems Biology Program, Sloan Kettering Institute, New York, United States.
Anthony PhillipakisBroad Institute of MIT and Harvard, Cambridge, United States.
Chris P PontingMRC Human Genetics Unit, MRC Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.ORCID 0000-0003-0202-7816
Stephen QuakeDepartment of Applied Physics and Department of Bioengineering, Stanford University, Stanford, United States.
Wolf ReikWellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Orit Rozenblatt-RosenBroad Institute of MIT and Harvard, Cambridge, United States.
Joshua SanesCenter for Brain Science and Department of Molecular and Cellular Biology, Harvard University, Cambridge, United States.ORCID 0000-0001-8926-8836
Rahul SatijaDepartment of Biology, New York University, New York, United States.ORCID 0000-0001-9448-8833
Ton N SchumacherDivision of Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Alex ShalekBroad Institute of MIT and Harvard, Cambridge, United States.
Ehud ShapiroDepartment of Computer Science and Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
Padmanee SharmaDepartment of Genitourinary Medical Oncology, Department of Immunology, MD Anderson Cancer Center, University of Texas, Houston, United States.
Jay W ShinDivision of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan.
Oliver StegleEMBL-European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Michael StrattonWellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Michael J T StubbingtonWellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Fabian J TheisInstitute of Computational Biology, German Research Center for Environmental Health, Helmholtz Center Munich, Neuherberg, Germany.
Matthias UhlenScience for Life Laboratory and Department of Proteomics, KTH Royal Institute of Technology, Stockholm, Sweden.
Alexander van OudenaardenHubrecht Institute and University Medical Center Utrecht, Utrecht, The Netherlands.
Allon WagnerDepartment of Electrical Engineering and Computer Science and the Center for Computational Biology, University of California, Berkeley, Berkeley, United States.
Fiona WattCentre for Stem Cells and Regenerative Medicine, King's College London, London, United Kingdom.ORCID 0000-0001-9151-5154
Jonathan WeissmanHoward Hughes Medical Institute, Chevy Chase, United States.ORCID 0000-0003-2445-670X
Barbara WoldDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Ramnik XavierBroad Institute of MIT and Harvard, Cambridge, United States.
Nir YosefRagon Institute of MGH, MIT and Harvard, Cambridge, United States.ORCID 0000-0001-9004-1225
Human Cell Atlas Meeting Participants
Funding
Virology CoreU19AI082630 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI GEORG Michael LAUER · 2009 to 2026
$48.1MPilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1991 to 2026
$35.3MA multimodal atlas of human brain cell typesU01MH114812 · NIMH · ALLEN INSTITUTE · PI LEIN, ED · 2017 to 2021
$19.2MDevelopment of tools for cell-type specific labeling of human and mouse neocortical neuronsRF1MH114126 · NIMH · ALLEN INSTITUTE · PI LEIN, ED, LEVI, BOAZ PIRIE · 2017 to 2017
$4.5MCell type selective viral tools to interrogate and correct non-human primate and human brain circuitryUG3MH120095 · NIMH · ALLEN INSTITUTE · PI KALUME, FRANCK K, LEIN, ED · 2020 to 2022
$3.8MHarnessing Csf-2 compartmentalized role on tissue resident phagocytes to uncouple anti-tumoral from pathological immunity induced by checkpoint inhibitorsR01CA190400 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MERAD, MIRIAM · 2015 to 2019
$1.9MCancer Research UK 22231Medical Research Council G1100073Medical Research Council MC_PC_12009Medical Research Council MC_PC_15075Medical Research Council MC_UU_00008/3Medical Research Council MC_UU_12008/1Medical Research Council MR/N024907/1NCI NIH HHS R01 CA190400NIAID NIH HHS U19 AI082630NIDDK NIH HHS P30 DK043351NIMH NIH HHS RF1 MH114126NIMH NIH HHS U01 MH114812NIMH NIH HHS UG3 MH120095Wellcome Trust 109965/Z/15/Z
Abstract
The recent advent of methods for high-throughput single-cell molecular profiling has catalyzed a growing sense in the scientific community that the time is ripe to complete the 150-year-old effort to identify all cell types in the human body. The Human Cell Atlas Project is an international collaborative effort that aims to define all human cell types in terms of distinctive molecular profiles (such as gene expression profiles) and to connect this information with classical cellular descriptions (such as location and morphology). An open comprehensive reference map of the molecular state of cells in healthy human tissues would propel the systematic study of physiological states, developmental trajectories, regulatory circuitry and interactions of cells, and also provide a framework for understanding cellular dysregulation in human disease. Here we describe the idea, its potential utility, early proofs-of-concept, and some design considerations for the Human Cell Atlas, including a commitment to open data, code, and community.
Indexed as
Atlases as TopicHuman BodyEukaryotic CellsHumansInternational Cooperationcell atlascell biologycomputational biologyhumanlineagemousescience forumsingle-cell genomicssystems biology
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