Evidence map›Paper›PMID 29206052›Full record

ArticleAmerican journal of respiratory and critical care medicine2018

Risk Trajectories of Readmission and Death in the First Year after Hospitalization for Chronic Obstructive Pulmonary Disease.

Peter K Lindenauer, Kumar Dharmarajan, Li Qin, Zhenqiu Lin, Andrea S Gershon, Harlan M Krumholz

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 4 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 4 syntheses or guidelines pooled it, 97 citations in OpenAlex.

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  17. Reply to HatipoğluAmerican journal of respiratory and critical care medicine · 2025
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  18. Article
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  20. Clinical Characteristics and Outcomes of Eosinophilic Exacerbations of COPD.International journal of chronic obstructive pulmonary disease · 2025
    Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Peter K Lindenauer1 Institute for Healthcare Delivery and Population Science and.
Kumar Dharmarajan4 Clover Health, Jersey City, New Jersey.
Li Qin6 Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut.
Zhenqiu Lin6 Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut.
Andrea S Gershon7 Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Harlan M Krumholz5 Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
Yale New Haven Hospital · USBaystate Medical Center · USSunnybrook Health Science Centre · CA

Funding

Geriatric Conditions and Readmission after Acute Myocardial InfarctionK23AG048331 · NIA · YALE UNIVERSITY · PI DHARMARAJAN, KUMAR · 2014 to 2017
$692k
Research and Mentoring in Comparative Effectiveness and Implementation ScienceK24HL132008 · NHLBI · BAYSTATE MEDICAL CENTER, INC. · PI LINDENAUER, PETER KYLE · 2016 to 2020
$574k
CIHRNHLBI NIH HHS K24 HL132008NIA NIH HHS K23 AG048331
6 · The paper itself

Abstract

rationaleCharacterization of the dynamic nature of posthospital risk in chronic obstructive pulmonary disease (COPD) is needed to provide counseling and plan clinical services.

objectivesTo analyze risk of readmission and death after discharge for COPD among Medicare beneficiaries aged 65 years and older and to determine the association between ventilator support and risk trajectory.

methodsWe computed daily absolute risks of hospital readmission and death for 1 year after discharge for COPD, stratified by ventilator support. We determined the time required for risks to decline by 50% from maximum daily values after discharge and for daily risks to plateau. We compared risks with those found in the general elderly population. MEASUREMENTS AND MAIN

resultsAmong 2,340,637 hospitalizations, the readmission rate at 1 year was 64.2%, including 63.5%, 66.0%, and 64.1% among those receiving invasive, noninvasive, and no ventilation, respectively. Among 1,283,069 hospitalizations, mortality at 1 year was 26.2%, including 45.7%, 41.8%, and 24.4% among those same respective groups. Daily risk of readmission declined by 50% within 28, 39, and 43 days and plateaued at 46, 54, and 61 days among those receiving invasive, noninvasive, and no ventilation, respectively. Risk of death declined by 50% by 3, 4, and 17 days and plateaued by 21, 18, and 24 days in the same respective groups. Risks of hospitalization and death were significantly higher after discharge for COPD than among the general Medicare population.

conclusionsDischarge from the hospital is associated with prolonged risks of readmission and death that vary with need for ventilator support. Interventions limited to the first month after discharge may be insufficient to improve longitudinal outcomes.

Indexed as

AgedAged, 80 and overCohort StudiesFemaleHospitalizationHumansLogistic ModelsMaleMedicarePatient DischargePatient ReadmissionPulmonary Disease, Chronic ObstructiveRisk AssessmentTime FactorsUnited Statesartificial respirationchronic obstructive pulmonary diseasemortalitynoninvasive ventilationpatient readmission

Identifiers

PMID29206052
PMCPMC5909167
OpenAlexW2772803279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.