Evidence map›Paper›PMID 29205335›Full record

ArticleJournal of anatomy2018

Melanomacrophage functions in the liver of the caecilian Siphonops annulatus.

Robson Campos Gutierre, Carlos Jared, Marta Maria Antoniazzi, Antonio Augusto Coppi, Mizue Imoto Egami

Open access · bronzeAbstract read
In one paragraph

Article in Journal of anatomy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Effects of exogenous elevation of corticosterone on immunity and the skin microbiome of eastern newts (Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Robson Campos GutierreDepartment of Morphology and Genetics, Federal University of São Paulo - Escola Paulista de Medicina, São Paulo, Brazil.ORCID 0000-0002-6101-3521
Carlos JaredCell Biology Laboratory, Instituto Butantan, São Paulo, Brazil.
Marta Maria AntoniazziCell Biology Laboratory, Instituto Butantan, São Paulo, Brazil.
Antonio Augusto CoppiFaculty of Health and Medical Sciences, School of Veterinary Medicine, University of Surrey, Guildford, Surrey, UK.
Mizue Imoto EgamiDepartment of Morphology and Genetics, Federal University of São Paulo - Escola Paulista de Medicina, São Paulo, Brazil.
Instituto Butantan · BRUniversidade Federal de São Paulo · BRUniversity of Surrey · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanomacrophages are phagocytes that synthesize melanin. They are found in the liver and spleen of ectothermic vertebrates, and in the kidney of fish. In agnathan and elasmobranch fish, melanomacrophages are seen as isolated cells, and forming clusters in all the other vertebrates. The natural phagocytic activity of melanomacrophages is poorly characterized, as most of the research works have focused on induced phagocytic activity only. Furthermore, little is known about amphibian melanomacrophages, mainly about those in caecilians - wormlike amphibians in the order of Gymnophiona, which is the least known group of terrestrial vertebrates. The present research work aimed at the structure and function of hepatic melanomacrophages of Siphonops annulatus, a species largely found in South America. We identified the role of these cells in the control of circulating basophils (pro-melanogenic cells), in the turnover of liver collagen stroma and in the hemocatheresis, interrelated physiological mechanisms.

Indexed as

AmphibiansAnimalsLiverMacrophagesMelaninsMelaninsamphibiabasophilcaecilianKupffer celllivermelaninmelanomacrophages

Identifiers

PMID29205335
PMCPMC5807933
OpenAlexW2772925946

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.