ArticleIl Giornale di chirurgia
Deep spinal infection in instrumented spinal surgery: diagnostic factors and therapy.
Article in Il Giornale di chirurgia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Surgical management of traumatic supra and infratentorial extradural hematomas: our experience and systematic literature review.Neurosurgical review · 2020Pooled it
- The efficacy of postoperative bracing after spine surgery for lumbar degenerative diseases: a systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2020Pooled it
- Surgical site infections: a comprehensive review.Journal of trauma and injury · 2025Article
- The Inflammatory Biomarkers Behavior Profile of Patients Following Elective Degenerative Spine Surgery and Differences Compared to Those Coursing With a Postoperative Spinal Infection: Protocol for a Systematic Review.JMIR research protocols · 2023Article
- Hypoalbuminemia and Elevated CRP are Risk Factors for Deep Infections and Urinary Tract Infections After Lumbar Spine Surgery in a Large Retrospective Patient Population.Global spine journal · 2023Article
- Spinal Surgery and Subsequent ESR and WBC Changes Pattern: A Single Center Prospective Study.Korean journal of neurotrauma · 2021Article
- Implications for diagnosis and treatment of peri-spinal implant infections from experiences in periprosthetic joint infections-a literature comparison and review.Journal of spine surgery (Hong Kong) · 2020Review
- A Retrospective Chart Review on the Role of Suppressive Therapy in the Management of Spinal Infections Involving Hardware.Open forum infectious diseases · 2020Article
- Intralesional and subarachnoid bleeding of a spinal schwannoma presenting with acute cauda equina syndrome.BMJ case reports · 2019Article
- Characteristics of treatment and outcome in elderly patients with brain glioblastoma: a retrospective analysis of case series.Acta clinica Croatica · 2019Article
- Ultra-early surgery in complete cervical spinal cord injury improves neurological recovery: A single-center retrospective study.Surgical neurology international · 2019Article
- Analysis of risk factors and postoperative predictors for recurrent lumbar disc herniation.Surgical neurology international · 2019Article
- Rare case of anterior cervical discectomy and fusion complication in a patient with Zenker's diverticulum.BMJ case reports · 2018Article
- Surgical treatment of aggressive vertebral hemangioma causing progressive paraparesis.Annals of medicine and surgery (2012) · 2018Article
- New or Blossoming Hemorrhagic Contusions After Decompressive Craniectomy in Traumatic Brain Injury: Analysis of Risk Factors.Frontiers in neurology · 2018Article
- Coil Extrusion into the Naso- and Oropharynx Ten Years after Internal Carotid Artery Pseudoaneurysm Embolization: A Case Report.Case reports in neurologyArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimPostoperative surgical site infections (SSI) are complication of spinal surgery. These complications may lead to a poor outcome with neurological deficits, spinal deformity and chronic pain. The purpose of this study is to explore the statistical value of diagnostic parameters and the proper therapy.
methodWe retrospectively reviewed 550 patients who underwent spinal instrumentation at our department from January 2011 to December 2015. The SSI was present in 16 patients out of 550 operated. Diagnostic criteria of SSI were the positivity of the surgical wound swab or blood culture, the clinical findings, positivity of laboratory tests and radiological elements. All patients had peri-operative antibiotic prophylaxis. Diagnostic laboratory findings were compared with a homogeneous control group of 16 patients and analyzed by univariate statistical analysis with Chi-square test for the discrete variables. P<0,05 was considered statistically significant.
resultsMatching the SSI patients with a group of control, fever was not statistically significant for diagnosis as number of leukocytes, neutrophils and lymphocytes. On the contrary values of ESR and CRP were statistically significant with p <0, 01. The hardware was removed only in 3 patients (18%) out of 16 SSI patients.
conclusionIn this study the statistically significant parameters to diagnose SSI are ESR and CRP values. The leucocytes count, number of lymphocytes and presence of fever integrates the data of ESR and CRP with no statistical significance. Most patients with SSI reach clinical healing with favorable outcome by means of target antibiotic therapy without hardware removal.
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