Evidence map›Paper›PMID 29204908›Full record

ArticleJournal of behavioral medicine2018

Posttraumatic stress disorder due to acute cardiac events and aversive cognitions towards cardiovascular medications.

S Ali Husain, Donald Edmondson, Marin Kautz, Redeana Umland, Ian M Kronish

Abstract read
In one paragraph

Article in Journal of behavioral medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Cardiac event-induced PTSD symptoms and continuous heart rate in coronary artery disease patients.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Posttraumatic stress and medication adherence in pediatric transplant recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Intervening on fear after acute cardiac events: Rationale and design of the INFORM randomized clinical trial.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2020
    Article
  14. Article
  15. Stressing Out About the Heart: A Narrative Review of the Role of Psychological Stress in Acute Cardiovascular Events.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2020
    Review
  16. Observational
  17. Article
  18. Identifying targets for cardiovascular medication adherence interventions through latent class analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2018
    Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

S Ali HusainDepartment of Medicine, Center for Behavioral Cardiovascular Health, Columbia University Medical Center, 622 West 168th Street, PH9-311, New York, NY, 10032, USA.
Donald EdmondsonDepartment of Medicine, Center for Behavioral Cardiovascular Health, Columbia University Medical Center, 622 West 168th Street, PH9-311, New York, NY, 10032, USA.
Marin KautzDepartment of Medicine, Center for Behavioral Cardiovascular Health, Columbia University Medical Center, 622 West 168th Street, PH9-311, New York, NY, 10032, USA.
Redeana UmlandDepartment of Medicine, Center for Behavioral Cardiovascular Health, Columbia University Medical Center, 622 West 168th Street, PH9-311, New York, NY, 10032, USA.
Ian M KronishDepartment of Medicine, Center for Behavioral Cardiovascular Health, Columbia University Medical Center, 622 West 168th Street, PH9-311, New York, NY, 10032, USA. ik2293@columbia.edu.
Columbia University Irving Medical Center · US

Funding

Impact of Social-Interpersonal Factors in the ER on PTSD/Cardiac OutcomesR01HL117832 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DAVIDSON, KARINA W., EDMONDSON, DONALD · 2013 to 2017
$3.1M
PTSD, Medication Adherence, and Prognosis after Acute Coronary SyndromesR01HL123368 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DAVIDSON, KARINA W., KRONISH, IAN MATTHEW · 2014 to 2017
$1.6M
NHLBI NIH HHS R01 HL117832NHLBI NIH HHS R01 HL123368
6 · The paper itself

Abstract

Posttraumatic stress disorder (PTSD) after acute medical events is associated with medication nonadherence. The mechanisms of PTSD-related nonadherence are poorly understood. We tested whether patients with elevated PTSD symptoms induced by suspected acute coronary syndrome (ACS) were more likely to have aversive cognitions towards cardiovascular medications. We enrolled a consecutive cohort of patients who presented to the emergency department with suspected ACS. One month after discharge, ACS-induced PTSD symptoms were assessed using the PTSD Checklist (PCL-S), and patients were asked "how often did" (1) "you miss your heart medication because you did not want to be reminded about your heart problem"; (2) "thinking about your heart medication make you feel nervous or anxious"; and (3) "thinking about your heart medication make you think about your risk for future heart problems." Logistic regression was used to determine the association between elevated PTSD symptoms and each aversive cognition, adjusting for age, sex, race, ethnicity, education, depression, and ACS status. Of 424 patients included, 15.8% had elevated PTSD symptoms (PCL-S ≥ 34). In adjusted analyses, higher PCL-S scores were associated with missing medications to avoid reminders of heart disease (OR 1.22 per 5-point PCL-S increase, 95%CI 1.07-1.40), as well as anxiety (OR 1.34, 95%CI 1.19-1.51) and thoughts of future risk (OR 1.19, 95%CI 1.08-1.32) when thinking about cardiovascular medications. We concluded that patients with elevated PTSD symptoms following suspected ACS were more likely to report aversive cognitions about their cardiovascular medications, suggesting that medications can act as traumatic reminders of the cardiac event and ongoing risk in this group.

Indexed as

Acute Coronary SyndromeAgedCognitionDepressionEmergency Service, HospitalFemaleHumansMaleMedication AdherenceMiddle AgedPatient DischargeStress Disorders, Post-TraumaticCardiovascular diseaseEnduring somatic threatMedication adherencePTSD

Identifiers

PMID29204908
PMCPMC5844812
OpenAlexW2771500079

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.