ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2018
Kinematically aligned total knee arthroplasty reduces knee adduction moment more than mechanically aligned total knee arthroplasty.
Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Mechanical versus kinematic alignment for total knee arthroplasty: a meta-analysis.Archives of orthopaedic and trauma surgery · 2025Pooled it
- Clinical relevance of joint line obliquity after high tibial osteotomy for medial knee osteoarthritis remains controversial: a systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Pooled it
- What is the "safe zone" for transition of coronal alignment from systematic to a more personalised one in total knee arthroplasty? A systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Pooled it
- Similar results with kinematic and mechanical alignment applied in total knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020Pooled it
- Six-degree-of-freedom knee motion during treadmill walking in mechanically and kinematically aligned TKA.Scientific reports · 2026Trial
- Modified kinematic alignment better restores plantar pressure distribution than mechanical alignment in total knee arthroplasty: a randomized controlled trial.Scientific reports · 2024Trial
- Coronal Plane Alignment of the Knee (CPAK) classification.The bone & joint journal · 2021Trial
- Kinematic Alignment in Total Knee Arthroplasty: Unresolved Challenges and Barriers to Overcome for Universal Application.Clinics in orthopedic surgery · 2026Review
- Kinematic alignment versus mechanical alignment in total knee arthroplasty: a systematic review and meta-analysis of medium to long-term outcomes.Musculoskeletal surgery · 2026Review
- Gait analysis after TKA: Do different alignment strategies lead to different outcomes? A systematic review.Musculoskeletal surgery · 2026Review
- Three-dimensional lower limb alignment in healthy Chinese adults: Gender-specific phenotypes and ethnic variations for personalised correction.Journal of experimental orthopaedics · 2026Article
- Unrestricted kinematic alignment total knee arthroplasty provides favourable five-year outcomes regardless of varus severity in Japanese patients.Journal of experimental orthopaedics · 2026Article
- Restricted kinematic alignment total knee arthroplasty using augmented reality technology to maintain limb alignment within targeted boundaries.Arthroplasty (London, England) · 2026Article
- Biomechanical analysis of surgical alignment and design in total knee arthroplasty.Archives of orthopaedic and trauma surgery · 2026Article
- Short-term Outcomes of Unrestricted Kinematic Alignment: Total Knee Arthroplasty With a Medial Pivot Implant: A Japanese Multicenter Study.Arthroplasty today · 2026Article
- Are current total knee arthroplasty implants tested and approved for personalised alignment?Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Article
- Preserving joint line orientation in TKA improves short- to mid-term outcomes: A systematic review and meta-analysis.Journal of experimental orthopaedics · 2025Review
- Component placement angles in total knee arthroplasty affect mid- to long-term clinical results: an average 8-year follow-up study.Archives of orthopaedic and trauma surgery · 2025Article
- Restoration of Joint Line Obliquity May Not Influence Lower Extremity Peak Frontal Plane Moments During Stair Negotiation.Bioengineering (Basel, Switzerland) · 2025Article
- Effect of posterior-stabilized and cruciate-retaining implants on three-dimensional kinematic characteristics after total knee arthroplasty.Joint diseases and related surgery · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeKnee adduction moment (KAM) has been recognized as a good clinical surrogate for medial tibiofemoral joint loading and is associated with implant durability after total knee arthroplasty (TKA). This study aimed to examine the effects of joint line obliquity in kinematically aligned TKA (KA-TKA) on KAM during gait.
methodsThe study enrolled 21 knees from 18 patients who underwent cylindrical axis reference KA-TKA and a matched group of 21 knees from 18 patients who underwent mechanically aligned (MA)-TKA as controls. Gait analyses were performed the day before TKA and at an overall mean of 2.6 years postoperatively. First peak KAM and variables associated with frontal knee kinetics were determined and compared between groups.
resultsIn KA-TKA, the proximal tibia was resected with 3.4° ± 1.5° of varus in relation to the mechanical axis, and the final femorotibial shaft axis was 176.7° ± 3.8° with KA-TKA and 174.4° ± 3.0° with MA-TKA. KAM was significantly smaller with KA-TKA than with MA-TKA (p < 0.032). Regarding variables affecting KAM, significant differences were evident between the two TKAs for knee adduction angle (p = 0.0021), lever arm (p = 0.028), and Δlever arm (p = 0.0001).
conclusionsIn KA-TKA, joint line obliquity reduced peak KAM during gait, despite slight varus limb alignment, and this reduced KAM in KA-TKA can tolerate constitutional varus alignment. In clinical settings, KA-TKA thus represents a promising technical option for patients with large coronal bowing of the shaft carrying a risk of increased KAM after TKA. LEVEL OF EVIDENCE: III.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.