Evidence map›Paper›PMID 29204662›Full record

ReviewMedizinische Klinik, Intensivmedizin und Notfallmedizin2019

Vasopressors for acute myocardial infarction complicated by cardiogenic shock.

R Prondzinsky, K Hirsch, L Wachsmuth, M Buerke, S Unverzagt

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

R ProndzinskyMedizinische Klinik I, Carl von Basedow-Klinikum Saalekreis gGmbH, Weisse Mauer 52, 06127, Merseburg, Germany. r.prondzinsky@klinikum-saalekreis.de.
K HirschInstitut für Medizinische Epidemiologie, Biometrie und Informatik, Martin Luther University Halle-Wittenberg, Halle/Saale, Germany.
L WachsmuthMedizinische Klinik I, Carl von Basedow-Klinikum Saalekreis gGmbH, Weisse Mauer 52, 06127, Merseburg, Germany.
M BuerkeKlinik für Kardiologie, Angiologie und internistische Intensivmedizin, Marienhospital, Siegen, Germany.
S UnverzagtInstitut für Medizinische Epidemiologie, Biometrie und Informatik, Martin Luther University Halle-Wittenberg, Halle/Saale, Germany.
Martin Luther University Halle-Wittenberg · DEKlinikum Coburg · DEMarienhospital Stuttgart · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several international evidence-based guidelines reveal the lack of evidence on the treatment of patients with acute myocardial infarction (AMI) complicated by cardiogenic shock (CS) for all recommended therapies. We included 6 studies with 842 eligible patients and one ongoing study. Three different adrenergic agents (norepinephrine, dopamine, epinephrine), vasopressin and the NOS inhibitor tilarginine were compared in 4 different combinations. On the small basis of all available evidence we can state that there is no evidence to use tilarginene, some evidence to avoid dopamine due to increased rates of arrhythmias, but some evidence, which suggests to prefer norepinephrine in comparison to epinephrine as vasopressor.

Indexed as

Myocardial InfarctionShock, CardiogenicHumansQuality of LifeTreatment OutcomeVasoconstrictor AgentsVasoconstrictor AgentsAcute coronary syndromeCardiogenic shockSystematic reviewVasoconstrictionVasopressor agents

Identifiers

PMID29204662
OpenAlexW2772081129

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.