Evidence map›Paper›PMID 29204577›Full record

ArticleWorld journal of otorhinolaryngology - head and neck surgery2017

Evidence for a 'preinvasive' variant of fungal sinusitis: Tissue invasion without angioinvasion.

Hassan Paknezhad, Nicole A Borchard, Greg W Charville, Noel F Ayoub, Garret W Choby, Andrew Thamboo, Jayakar V Nayak

Abstract read
In one paragraph

Article in World journal of otorhinolaryngology - head and neck surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Isolated Acute Sphenoid Fungal Sinusitis with Cavernous Sinus Thrombosis: Our Experience.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hassan PaknezhadDivision of Rhinology, Department of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, USA.
Nicole A BorchardDivision of Rhinology, Department of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, USA.
Greg W CharvilleDivision of Rhinology, Department of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, USA.
Noel F AyoubDivision of Rhinology, Department of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, USA.
Garret W ChobyDivision of Rhinology, Department of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, USA.
Andrew ThambooDivision of Rhinology, Department of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, USA.
Jayakar V NayakDivision of Rhinology, Department of Otolaryngology - Head and Neck Surgery, Stanford University School of Medicine, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical experience has suggested the existence of an intermediate form of fungal sinusitis between the categories of non-invasive fungal sinusitis (non-IFS) and invasive fungal sinusitis (IFS). This fungal sinusitis variant demonstrates unhealthy mucosa by endoscopy with fungal invasion, but lacks angioinvasion microscopically, representing what clinically behaves as a 'pre-invasive' subtype of fungal sinusitis. Unlike non-IFS disease, patients with pre-invasive fungal sinusitis were still felt to require anti-fungal medications due to histologic presence of invasive fungus. While sharing some clinical features of IFS, these 'intermediate' patients were successfully spared extended and repeated surgical debridements given the microscopic findings, and have been successfully treated with shorter courses of antifungal therapy. These select patients have had favorable outcomes when managed in a judicious and semi-aggressive manner, in an undefined zone between the treatments for routine fungal ball and aggressive IFS.

Indexed as

Antifungal therapyChronic rhinosinusitisFungal ballFungal sinusitisIFSImmunocompromisedImmunosuppressedInvasive fungal sinusitisVisual loss

Identifiers

PMID29204577
PMCPMC5683596

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.