Evidence map›Paper›PMID 29204536›Full record

ReviewWorld journal of otorhinolaryngology - head and neck surgery2015

Clinical consequences and economic costs of untreated obstructive sleep apnea syndrome.

Melissa Knauert, Sreelatha Naik, M Boyd Gillespie, Meir Kryger

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of otorhinolaryngology - head and neck surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 139 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
139citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

139 citing papers in PubMed, 11 syntheses or guidelines pooled it.

  1. Guideline
  2. Racial and Ethnic Disparities in the Diagnosis and Treatment of Obstructive Sleep Apnea: A Systematic Review.International journal of environmental research and public health · 2026
    Pooled it
  3. Guideline
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  6. Validation of the STOP questionnaire as a screening tool for OSA among different populations: a systematic review and meta-regression analysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Pooled it
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  12. Trial
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  15. Diagnosis and management of sleep apnea by a clinical nurse: a noninferiority randomized clinical trial.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Trial
  16. Treatment for patients with sleep apnea on opioids for chronic pain: results of the OpSafe trial.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Trial
  17. Article
  18. Article
  19. Article
  20. Article

79 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Melissa KnauertSection of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, CT, USA.
Sreelatha NaikSection of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, CT, USA.
M Boyd GillespieOtolaryngology - Head & Neck Surgery, Medical University of South Carolina, Charleston, SC, USA.
Meir KrygerSection of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, CT, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo provide an overview of the healthcare and societal consequences and costs of untreated obstructive sleep apnea syndrome. DATA SOURCES: PubMed database for English-language studies with no start date restrictions and with an end date of September 2014.

methodsA comprehensive literature review was performed to identify all studies that discussed the physiologic, clinical and societal consequences of obstructive sleep apnea syndrome as well as the costs associated with these consequences. There were 106 studies that formed the basis of this analysis.

conclusionsUndiagnosed and untreated obstructive sleep apnea syndrome can lead to abnormal physiology that can have serious implications including increased cardiovascular disease, stroke, metabolic disease, excessive daytime sleepiness, work-place errors, traffic accidents and death. These consequences result in significant economic burden. Both, the health and societal consequences and their costs can be decreased with identification and treatment of sleep apnea. IMPLICATIONS FOR PRACTICE: Treatment of obstructive sleep apnea syndrome, despite its consequences, is limited by lack of diagnosis, poor patient acceptance, lack of access to effective therapies, and lack of a variety of effective therapies. Newer modes of therapy that are effective, cost efficient and more accepted by patients need to be developed.

Indexed as

Continuous positive airway pressureCostMandibular advancement deviceObstructive sleep apnea syndrome

Identifiers

PMID29204536
PMCPMC5698527

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.