ArticleTobacco regulatory science2017
Effect of Flavors and Modified Risk Messages on E-cigarette Abuse Liability.
Article in Tobacco regulatory science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The Role of Nicotine and Flavor in the Abuse Potential and Appeal of Electronic Cigarettes for Adult Current and Former Cigarette and Electronic Cigarette Users: A Systematic Review.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022Pooled it
- Sensitivity of hypothetical purchase task indices when studying substance use: A systematic literature review.Preventive medicine · 2019Pooled it
- Impact of non-menthol flavours in e-cigarettes on perceptions and use: an updated systematic review.BMJ open · 2019Pooled it
- Abuse Liability of Electronic Cigarettes in Never-Smoking Electronic Cigarette Users.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Trial
- Targeted Versus Nontargeted Communication About Electronic Nicotine Delivery Systems in Three Smoker Groups.International journal of environmental research and public health · 2018Trial
- Assessment of nicotine pharmacokinetics and abuse liability in randomized, crossover studies of Vuse Alto electronic nicotine delivery systems.Frontiers in pharmacology · 2026Article
- Assessment of human abuse potential of an unflavored, sucralose-sweetened electronic cigarette in combustible cigarette smokers.Experimental and clinical psychopharmacology · 2024Article
- The electronic nicotine delivery system (ENDS) purchase task: Are results sensitive to price framing?Experimental and clinical psychopharmacology · 2023Article
- Characterizing different-flavored e-cigarette solutions from user-reported sensory attributes and appeal.Experimental and clinical psychopharmacology · 2023Article
- Behavioral economic assessment of abuse liability for Black & Mild cigar flavors among young adults.Experimental and clinical psychopharmacology · 2022Article
- Associations Between Perceptions of e-Cigarette Harmfulness and Addictiveness and the Age of E-Cigarette Initiation Among the Population Assessment of Tobacco and Health (PATH) Youth.Tobacco use insights · 2022Article
- Indicators of dependence and efforts to quit vaping and smoking among youth in Canada, England and the USA.Tobacco control · 2021Article
- Associations Between Peer Use, Costs and Benefits, Self-Efficacy, and Adolescent E-cigarette Use.Journal of pediatric psychology · 2021Article
- Effect of e-cigarette advertisement themes on hypothetical e-cigarette purchasing in price-responsive adolescents.Addiction (Abingdon, England) · 2020Article
- "I cannot live without my vape": Electronic cigarette user-identified indicators of vaping dependence.Drug and alcohol dependence · 2020Article
- Abuse liability of electronic cigarettes in men who are experienced electronic cigarette users.Experimental and clinical psychopharmacology · 2020Article
- 'The lesser devil you don't know': a qualitative study of smokers' responses to messages communicating comparative risk of electronic and combusted cigarettes.Tobacco control · 2020Article
- An experimental study of messages communicating potential harms of electronic cigarettes.PloS one · 2020Article
- Abuse liability assessment of an electronic cigarette in combustible cigarette smokers.Experimental and clinical psychopharmacology · 2019Article
- Testing messages about comparative risk of electronic cigarettes and combusted cigarettes.Tobacco control · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
objectivesTo measure e-cigarettes' abuse liability compared to conventional tobacco cigarettes under flavor and message conditions amenable to regulation.
methodsTwo studies used 2×2 within-subjects designs with factors of e-cigarette flavor (Study 1: tobacco vs. menthol; Study 2: cherry vs. unflavored) and message (Study 1: reduced harm vs. no message; Study 2: reduced exposure to carcinogens vs. no message) with cigarette smokers (N(total) = 36). Linear mixed effects models assessed abuse liability for tobacco products. Outcomes included the price after which consumption is zero (the maximum amount participants would pay for a tobacco product) from the multiple choice procedure (MCP) and cigarette purchase task (CPT) and demand elasticity (price sensitivity) from the CPT.
resultsIn the MCP, the price where consumption reached zero was significantly lower in all e-cigarette conditions except tobacco flavor (message or no message) compared to cigarettes (p < .05 each). Demand elasticity was significantly higher for menthol/no message and unflavored/reduced exposure message conditions relative to cigarettes (p < .05 each).
conclusionsFlavors and modified risk messages included with e-cigarettes may affect e-cigarette abuse liability among smokers, suggesting regulatory pathways to influence demand for conventional and alternative tobacco products.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.