Evidence map›Paper›PMID 29204308›Full record

ArticleSurgical neurology international2017

Aplasia cutis congenita: Two case reports and discussion of the literature.

Alexandros Blionas, Dimitrios Giakoumettis, Elias Antoniades, Evangelos Drosos, Andreas Mitsios, Sotirios Plakas, Georgios Sfakianos, Marios S Themistocleous

Erratum issuedOpen access · hybridAbstract readCase Reports
In one paragraph

Article in Surgical neurology international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 42 citations in OpenAlex.

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  14. Membranous aplasia cutis congenita in trisomy 18.Italian journal of pediatrics · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Alexandros BlionasDepartment of Neurosurgery, Asklepieion Hospital of Voula, Voula, Greece.
Dimitrios GiakoumettisDepartment of Neurosurgery, University of Athens Medical School, "Evangelismos" General Hospital, Athens, Greece.
Elias AntoniadesDepartment of Neurosurgery, University of Thessaloniki Medical School, "AHEPA" University Hospital, Thessaloniki, Greece.
Evangelos DrososDepartment of Neurosurgery, University of Athens Medical School, "Evangelismos" General Hospital, Athens, Greece.
Andreas MitsiosDepartment of Neurosurgery, Children's Hospital "Agia Sofia", Athens, Greece.
Sotirios PlakasDepartment of Neurosurgery, Kings College Hospital NHS Foundation Trust, London, UK.
Georgios SfakianosDepartment of Neurosurgery, Children's Hospital "Agia Sofia", Athens, Greece.
Marios S ThemistocleousDepartment of Neurosurgery, Children's Hospital "Agia Sofia", Athens, Greece.
Iaso Children’s Hospital · GRNational and Kapodistrian University of Athens · GRAHEPA University Hospital · GRGeneral Hospital Asklepieio Voulas · GRKing's College Hospital NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Aplasia cutis congenita (ACC) is a part of a heterogeneous group of conditions characterized by the congenital absence of epidermis, dermis, and in some cases, subcutaneous tissues or bone usually involving the scalp vertex. There is an estimated incidence of 3 in 10,000 births resulting in a total number of 500 reported cases to date. The lesions may occur on every body surface although localized scalp lesions form the most frequent pattern (70%). Complete aplasia involving bone defects occurs in approximately 20% of cases. ACC can occur as an isolated defect or can be associated with a number of other congenital anomalies such as limb anomalies or embryologic malformations. In patients with large scalp and skull defects, there is increased risk of infection and bleeding along with increased mortality and therefore prompt and effective management is advised. Case Description: We describe two cases of ACC, involving a 4 × 3 cm defect managed conservatively and a larger 10 × 5 cm defect managed surgically with the use of a temporo-occipital scalp flap. Both cases had an excellent outcome. Conclusions: Multiple treatment regimens exist for ACC, but there is no consensus on treatment strategies. Conservative treatment has been described and advocated, but many authors have emphasized the disadvantages of this treatment modality. Decision between conservative and surgical management must be individualized according to lesion size and location.

Indexed as

Aplasia cutis congenitacongenital anomaliescranial reconstructionscalp reconstruction

Identifiers

PMID29204308
PMCPMC5691551
OpenAlexW2770542328

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.