ReviewOxidative medicine and cellular longevity2017
Oxidative Stress Modulation and ROS-Mediated Toxicity in Cancer: A Review on
Review in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 111 citations in OpenAlex.
- Ameliorative Role of fenugreek Oil Against Lead Acetate Trihydrate-Induced Hepatic, Renal and Testicular Injury in Wistar Albino Rats: Insights into Bcl-2 Expression and sodium/potassium balance.Biological trace element research · 2026Article
- Cytotoxic Effects of Medicinal Plant Extracts on HeLa Cells via Redox Imbalance, L-Arginine Metabolic Reprogramming, and Glycolytic Suppression.Cell biochemistry and function · 2026Article
- Plant‑mediated silver quantum dots from Drimia maritima: antioxidant modulation and ROS‑induced apoptosis in breast cancer cells.Scientific reports · 2026Article
- Article
- Ethanolic extract of Otostegia fruticosa induces ROS-dependent apoptosis and reduces migration of MDA-MB-231 cells in vitro.PloS one · 2026Article
- Anticancer activity of nanoemulsion formulation of Chicorium intybus L. seed extract on human breast cancer cells.Scientific reports · 2025Article
- Influence of pigment epithelium-derived factors on HBiological research · 2025Article
- Bioactive Aromatic Plant Extracts Modulate Metabolism and Inflammation in HeLa Cells.Molecules (Basel, Switzerland) · 2025Article
- Characterization and Phenolic Profiling of AnticandidalACS omega · 2025Article
- Role of Fruit-Derived Antioxidants in Fighting Cancer: A Narrative Review.Indian journal of clinical biochemistry : IJCB · 2025Review
- Assessment of the Nutraceutical Properties of Wild Strawberry (Fragaria vesca L.) Extracts on Human Colorectal Cell Lines.Molecular nutrition & food research · 2025Article
- Potential Antimicrobial and Cytotoxic Activity ofAntibiotics (Basel, Switzerland) · 2024Article
- [The role and the molecular mechanism of abietic acid in the proliferation, invasion and migration of cisplatin-resistant nasopharyngeal carcinoma cells].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2024Article
- Antioxidant Properties and Vasorelaxant Mechanism of Aqueous ExtractBioMed research international · 2024Article
- Chasing Graphene-Based Anticancer Drugs: Where are We Now on the Biomedical Graphene Roadmap?International journal of nanomedicine · 2024Review
- The Physiological and Pathological Role of Acyl-CoA Oxidation.International journal of molecular sciences · 2023Review
- Anti-oxidant and Anti-inflammatory Effects of Ethanol Extract from Polygala sibirica L. var megalopha Fr. on Lipopolysaccharide-Stimulated RAW264.7 Cells.Chinese journal of integrative medicine · 2023Article
- An In Silico Molecular Modelling-Based Prediction of Potential Keap1 Inhibitors fromMolecules (Basel, Switzerland) · 2023Article
- Tinospora sinensis (Lour.) Merr alkaloid rich extract induces colon cancer cell death via ROS mediated, mTOR dependent apoptosis pathway: "an in-vitro study".BMC complementary medicine and therapies · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Medicinal and aromatic plants (MAPs) are known and have been long in use for a variety of health and cosmetics applications. Potential pharmacological usages that take advantage of bioactive plant-derived compounds' antimicrobial, antifungal, anti-inflammatory, and antioxidant properties are being developed and many new ones explored. Some phytochemicals could trigger ROS-mediated cytotoxicity and apoptosis in cancer cells. A lot of effort has been put into investigating novel active constituents for cancer therapeutics. While other plant-derived compounds might enhance antioxidant defenses by either radical scavenging or stimulation of intracellular antioxidant enzymes, the generation of reactive oxygen species (ROS) leading to oxidative stress is one of the strategies that may show effective in damaging cancer cells. The biochemical pathways involved in plant-derived bioactive compounds' properties are complex, and
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.