ArticleJournal of contemporary brachytherapy2017
Comparison of dose volume parameters evaluated using three forward planning - optimization techniques in cervical cancer brachytherapy involving two applicators.
Article in Journal of contemporary brachytherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Effect of applicator removal from target volume for cervical cancer patients treated with Venezia high-dose-rate brachytherapy applicator.Journal of contemporary brachytherapy · 2022Article
- Outcomes of patients with cervical cancer treated with low- or high-dose rate brachytherapy after concurrent chemoradiation.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2021Article
- Preliminary results of modified interstitial MIAMI brachytherapy applicator for treatment of upper and apical vaginal tumors.Journal of contemporary brachytherapy · 2020Article
- Clinical and dosimetric consequences of imperfect applicator insertion in cervical cancer brachytherapy.Journal of contemporary brachytherapy · 2018Article
- Dosimetric evaluation of Point A and volume-based high-dose-rate plans: a single institution study on adaptive brachytherapy planning for cervical cancer.Journal of contemporary brachytherapy · 2018Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study is intended to compare dose-volume parameters evaluated using different forward planning- optimization techniques, involving two applicator systems in intracavitary brachytherapy for cervical cancer. It looks for the best applicator-optimization combination to fulfill recommended dose-volume objectives in different high-dose-rate (HDR) fractionation schedules. MATERIAL AND
methodsWe used tandem-ring and Fletcher-style tandem-ovoid applicator in same patients in two fractions of brachytherapy. Six plans were generated for each patient utilizing 3 forward optimization techniques for each applicator used: equal dwell weight/times ('no optimization'), 'manual dwell weight/times', and 'graphical'. Plans were normalized to left point A and dose of 8 Gy was prescribed. Dose volume and dose point parameters were compared.
resultsWithout graphical optimization, maximum width and thickness of volume enclosed by 100% isodose line, dose to 90%, and 100% of clinical target volume (CTV); minimum, maximum, median, and average dose to both rectum and bladder are significantly higher with Fletcher applicator. Even if it is done, dose to both points B, minimum dose to CTV, and treatment time; dose to 2 cc (D
conclusionsFletcher applicator generates higher dose to both CTV and organs at risk (2 cc volumes) after all optimization techniques. Dose restriction to rectum is possible using graphical optimization only during selected HDR fractionation schedules. Bladder always receives dose higher than recommended, and 2 cc sigmoid colon always gets permissible dose. Contrarily, graphical optimization with ring applicators fulfills all dose volume objectives in all HDR fractionations practiced.
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