Evidence map›Paper›PMID 29204163›Full record

ArticleJournal of contemporary brachytherapy2017

Efficacy of single-stage breast-conserving treatment using multicatheter partial breast brachytherapy evaluated by GEC-ESTRO phase 3 trial.

Kazuhiko Sato, Hiromi Fuchikami, Masahiro Kato, Takahiro Shimo, Jun Kubota, Naoko Takeda, Yuko Inoue, Hiroshi Seto, Tomohiko Okawa

Open access · goldAbstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kazuhiko SatoDepartment of Breast Oncology, Tokyo-West Tokushukai Hospital, Tokyo.
Hiromi FuchikamiDepartment of Breast Oncology, Tokyo-West Tokushukai Hospital, Tokyo.
Masahiro KatoDepartment of Radiation Oncology, Tokyo-West Tokushukai Hospital, Tokyo.
Takahiro ShimoDepartment of Radiation Oncology, Tokyo-West Tokushukai Hospital, Tokyo.
Jun KubotaDepartment of Radiation Oncology, Tokyo-West Tokushukai Hospital, Tokyo.
Naoko TakedaDepartment of Breast Oncology, Tokyo-West Tokushukai Hospital, Tokyo.
Yuko InoueInoue Ladies Clinic, Tokyo.
Hiroshi SetoSeto Hospital, Saitama.
Tomohiko OkawaPreventive Medicine Center, Sano City Hospital, Tochigi, Japan.
Fukuoka Tokushukai Hospital · JPInoue Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe GEC-ESTRO has reported the equivalent outcomes of partial breast irradiation (PBI) using multicatheter interstitial brachytherapy (MCB) to whole breast irradiation (WBI) in breast-conserving therapy (BCT). We performed single-stage BCT with partial breast brachytherapy by intraoperative catheter placement. After the categorization of patients into inclusion and exclusion criteria on this trial, our databases were evaluated in order to translate it to Japanese patients. MATERIAL AND

methodsPatients undergoing BCT were retrospectively examined between November 2007 and December 2015. The technique is an open-cavity implant with a dose of 32 Gy in 8 fractions. The 4-year clinical outcomes of MCB-PBI were evaluated in the 2 distinct categories, and the comparison of the outcomes of MCB-PBI with WBI was performed in patients with unfavorable features.

resultsOf a total of 501 lesions undergoing BCT, 301 lesions were treated with MCB-PBI and 200 lesions with WBI. At the median follow-up time of 52 months, the 4-year rate of ipsilateral breast tumor recurrence (IBTR)-free, disease-free (DFS), and overall survival (OS) in patients with MCB-PBI and WBI were 98.9% vs. 98.0% (

conclusionsSingle-stage BCT using MCB-PBI offered similar tumor control rates compering to WBI. However, further research is needed to define the benefit for patients with an exclusion criteria.

Indexed as

breast cancerinterstitial brachytherapyipsilateral breast tumor recurrencepartial breast irradiationwhole breast irradiation

Identifiers

PMID29204163
PMCPMC5705836
OpenAlexW2767499712

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.