Evidence map›Paper›PMID 29204096›Full record

ReviewCentral-European journal of immunology2017

Interference RNA in immune-mediated oral diseases - minireview.

Raghu Dhanapal, Sreepallavi Somasundarapandian, Sosroseno Wihaskoro, Ranganathan Kannan, Govind Rajkumar, Ramasamy Chidambaram

Open access · goldAbstract readReview
In one paragraph

Review in Central-European journal of immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. RNA Interference Ex Vivo.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Raghu DhanapalAimst Dental Institute, Aimst University, Bedong, Malaysia.
Sreepallavi SomasundarapandianAimst Dental Institute, Aimst University, Bedong, Malaysia.
Sosroseno WihaskoroAimst Dental Institute, Aimst University, Bedong, Malaysia.
Ranganathan KannanRagas Dental College, Chennai, Malaysia.
Govind RajkumarVishnu Dental College, Bhimavaram, Malaysia.
Ramasamy ChidambaramAimst Dental Institute, Aimst University, Bedong, Malaysia.
AIMST University · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune-mediated oral disorders are characterised by their chronicity, and some are refractory to treatment. Interference RNA (iRNA) has been implicated in the underlying mechanism of such immune-mediate oral and refractory inflammatory oral diseases. iRNA-based understanding of the mechanism in these diseases may help to produce non-invasive diagnostic methodologies and treatment modalities of such drug non-responsive diseases. Oral lesions in these immune-mediated diseases can precede the occurrence of lesions in other regions of the body. The early diagnosis and treatment of these drug non-responsive diseases might benefit the patient by reducing chronicity and probably even resolving the disease. This aim of the present minireview is to give an overview of the possible implications of iRNA on the pathogenesis, diagnosis, and treatments of immune-mediated and inflammatory oral diseases. The manuscript can form the framework for research on iRNA in these immune-mediated oral disorders.

Indexed as

Immune disordersoral manifestationsRNA interferenceRNAi therapies

Identifiers

PMID29204096
PMCPMC5708212
OpenAlexW2769862872

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.