Evidence map›Paper›PMID 29204058›Full record

ArticleWorld journal of gastroenterology2017

Diversity of bacterial lactase genes in intestinal contents of mice with antibiotics-induced diarrhea.

Cheng-Xing Long, Lu He, Yan-Fang Guo, Ya-Wei Liu, Nen-Qun Xiao, Zhou-Jin Tan

Open access · bronzeAbstract read
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Diarrhea Caused by High-Fat and High-Protein Diet Was Associated With Intestinal Lactase-Producing Bacteria.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Gut Microbiota and Diarrhea: An Updated Review.Frontiers in cellular and infection microbiology · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Bacterial Lactase Gene Characteristics in Intestinal Contents of Antibiotic-Associated Diarrhea Mice Treated with Debaryomyces hansenii.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Cheng-Xing LongLu-He, Yan-Fang Guo, Ya-Wei Liu, Nen-Qun Xiao, Zhou-Jin Tan, Department of Microbiology, Hunan University of Chinese Medicine, Changsha 410208, Hunan Province, China.
Lu He
Yan-Fang Guo
Ya-Wei Liu
Nen-Qun Xiao
Zhou-Jin Tan
Hunan University of Humanities, Science and Technology · CNHunan University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the diversity of bacterial lactase genes in the intestinal contents of mice with antibiotics-induced diarrhea.

methodsFollowing 2 d of adaptive feeding, 12 specific pathogen-free Kunming mice were randomly divided into the control group and model group. The mouse model of antibiotics-induced diarrhea was established by gastric perfusion with mixed antibiotics (23.33 mL·kg

resultsOTUs were 871 and 963 in the model group and control group, respectively, and 690 of these were identical. There were significant differences in Chao1 and ACE indices between the two groups (

conclusionAntibiotics reduce the diversity of bacterial lactase genes in the intestinal contents, decrease the abundance of lactase gene, change the lactase gene strains, and transform their structures.

Indexed as

Genes, BacterialAnimalsAnti-Bacterial AgentsDiarrheaFemaleGastrointestinal MicrobiomeLactaseMaleMiceRandom AllocationAnti-Bacterial AgentsLactaseAntibiotics-induced diarrheaGene diversityHigh-throughput sequencingIntestinal bacteriaLactase genes

Identifiers

PMID29204058
PMCPMC5698251
OpenAlexW2767813508

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.