ArticleScientific reports2017
Cortical organization restored by cochlear implantation in young children with single sided deafness.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- Benefits of bilateral cochlear implantation in children: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Pooled it
- Implantable Devices for Single-Sided Deafness and Conductive or Mixed Hearing Loss: A Health Technology Assessment.Ontario health technology assessment series · 2020Pooled it
- Rehabilitation Strategies for Pediatric Single-Sided Deafness, Including Children with Asymmetric Hearing Loss: A Systematic Review.Audiology research · 2026Review
- Preoperative Hearing Aids Improve Outcomes of Cochlear Implantation.Clinical and experimental otorhinolaryngology · 2026Article
- Moving, Seeing, Hearing, Smelling and Tasting: How Sensory-Motor Experiences Shape Early Cognitive Development.Behavioral sciences (Basel, Switzerland) · 2026Review
- Hearing Outcomes in Children with Unilateral Hearing Loss. The Benefits of Rehabilitative Strategies: Preliminary Results.Audiology research · 2025Article
- Cochlear implantation for children with single-sided deafness: parents' perspectives.Journal of the Royal Society of New Zealand · 2025Article
- Cochlear implantation in adults with acquired single-sided deafness improves cortical processing and comprehension of speech presented to the non-implanted ears: a longitudinal EEG study.Brain communications · 2025Article
- Dissociated Representation of Binaural Cues in Single-Sided Deafness: Implications for Cochlear Implantation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Bidirectional remodeling of the central auditory system caused by unilateral auditory deprivation.Frontiers in neurology · 2024Review
- Congenital Cytomegalovirus and Hearing Loss: The State of the Art.Journal of clinical medicine · 2023Review
- A cortical biomarker of audibility and processing efficacy in children with single-sided deafness using a cochlear implant.Scientific reports · 2023Article
- A Prospective Study of Genetic Variants in Infants with Congenital Unilateral Sensorineural Hearing Loss.Journal of clinical medicine · 2023Article
- Cortical imbalance following delayed restoration of bilateral hearing in deaf adolescents.Human brain mapping · 2022Article
- A Prospective Study of Etiology and Auditory Profiles in Infants with Congenital Unilateral Sensorineural Hearing Loss.Journal of clinical medicine · 2022Article
- Side-of-Implantation Effect on Functional Asymmetry in the Auditory Cortex of Single-Sided Deaf Cochlear-Implant Users.Brain topography · 2022Article
- Visual statistical learning in deaf and hearing infants and toddlers.Infancy : the official journal of the International Society on Infant Studies · 2022Article
- Lateralization Pattern of the Weber Tuning Fork Test in Longstanding Unilateral Profound Hearing Loss: Implications for Cochlear Implantation.Audiology research · 2022Article
- The Importance of Access to Bilateral Hearing through Cochlear Implants in Children.Seminars in hearing · 2021Review
- Long-term results of cochlear implantation in children with congenital single-sided deafness.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Early treatment of single sided deafness in children has been recommended to protect from neurodevelopmental preference for the better hearing ear and from social and educational deficits. A fairly homogeneous group of five young children (≤3.6 years of age) with normal right sided hearing who received a cochlear implant to treat deafness in their left ears were studied. Etiology of deafness was largely cytomegalovirus (n = 4); one child had an enlarged vestibular aqueduct. Multi-channel electroencephalography of cortical evoked activity was measured repeatedly over time at: 1) acute (0.5 ± 0.7 weeks); 2) early chronic (1.1 ± 0.2 months); and 3) chronic (5.8 ± 3.4 months) cochlear implant stimulation. Results indicated consistent responses from the normal right ear with marked changes in activity from the implanted left ear. Atypical distribution of peak amplitude activity from the implanted ear at acute stimulation marked abnormal lateralization of activity to the ipsilateral left auditory cortex and recruitment of extra-temporal areas including left frontal cortex. These abnormalities resolved with chronic implant use and contralateral aural preference emerged in both auditory cortices. These findings indicate that early implantation in young children with single sided deafness can rapidly restore bilateral auditory input to the cortex needed to improve binaural hearing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.