Evidence map›Paper›PMID 29203701›Full record

ReviewGenetics2017

Regulation of Carbohydrate Energy Metabolism in

Jaakko Mattila, Ville Hietakangas

Abstract readReview
In one paragraph

Review in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Lipid Metabolism in Relation to Carbohydrate Metabolism.Advances in experimental medicine and biology · 2026
    Review
  9. Article
  10. The insulin-like peptides Dilp2 and Dilp6 exhibit divergent responses to dietary sugar and protein inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. IntegratingFrontiers in pharmacology · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jaakko MattilaGerman Cancer Research Center (DKFZ), Heidelberg, Germany.
Ville HietakangasDepartment of Biosciences, University of Helsinki, Finland ville.hietakangas@helsinki.fi.ORCID 0000-0002-9900-7549

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbohydrate metabolism is essential for cellular energy balance as well as for the biosynthesis of new cellular building blocks. As animal nutrient intake displays temporal fluctuations and each cell type within the animal possesses specific metabolic needs, elaborate regulatory systems are needed to coordinate carbohydrate metabolism in time and space. Carbohydrate metabolism is regulated locally through gene regulatory networks and signaling pathways, which receive inputs from nutrient sensors as well as other pathways, such as developmental signals. Superimposed on cell-intrinsic control, hormonal signaling mediates intertissue information to maintain organismal homeostasis. Misregulation of carbohydrate metabolism is causative for many human diseases, such as diabetes and cancer. Recent work in

Indexed as

AnimalsCarbohydrate MetabolismCarbohydratesDrosophila melanogasterEnergy MetabolismGlucoseHomeostasisHumansInsulinMetabolic DiseasesSignal TransductionCarbohydratesGlucoseInsulingene regulationglucoseinsulinmetabolismnutrient sensing

Identifiers

PMID29203701
PMCPMC5714444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.