ArticleProceedings of the National Academy of Sciences of the United States of America2018
Methylprednisolone acetate induces, and Δ7-dafachronic acid suppresses,
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In one paragraph
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
9.7field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 62 citations in OpenAlex.
- Development of Dirofilaria immitis adult worms in NSG mice, detection of parasite-derived microRNA and comparative analysis of laboratory isolates.Scientific reports · 2026Article
- A dual role of lysophosphatidic acid type 2 receptor (LPAR2) in nonsteroidal anti-inflammatory drug-induced mouse enteropathy.Acta pharmacologica Sinica · 2024Article
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- Establishment of an Animal Model Scheme ofPathogens (Basel, Switzerland) · 2023Article
- Route of dexamethasone administration influences parasite burden inJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023Article
- A rodent model for Dirofilaria immitis, canine heartworm: parasite growth, development, and drug sensitivity in NSG mice.Scientific reports · 2023Article
- Host genetic backgrounds: the key to determining parasite-host adaptation.Frontiers in cellular and infection microbiology · 2023Review
- Dirofilariasis mouse models for heartworm preclinical research.Frontiers in microbiology · 2023Article
- Immune-responsive biodegradable scaffolds for enhancing neutrophil regeneration.Bioengineering & translational medicine · 2023Article
- Immunomodulatory and biological properties of helminth-derived small molecules: Potential applications in diagnostics and therapeutics.Frontiers in parasitology · 2022Review
- Seroprevalence of Strongyloides infection among steroid recipients in a tertiary care centre in North India.Le infezioni in medicina · 2022Article
- Characterization of the endogenous DAF-12 ligand and its use as an anthelmintic agent ineLife · 2021Article
- Strongyloides stercoralis and HTLV-1 coinfection in CD34+ cord blood stem cell humanized mice: Alteration of cytokine responses and enhancement of larval growth.PLoS neglected tropical diseases · 2021Article
- Identification of a nuclear receptor/coactivator developmental signaling pathway in the nematode parasiteProceedings of the National Academy of Sciences of the United States of America · 2021Article
- Exposure to dexamethasone modifies transcriptomic responses of free-living stages of Strongyloides stercoralis.PloS one · 2021Article
- Human T-cell Leukemia Virus Type 1 andPathogens (Basel, Switzerland) · 2020Review
- Dafachronic acid and temperature regulate canonical dauer pathways during Nippostrongylus brasiliensis infectious larvae activation.Parasites & vectors · 2020Article
- The Two Faces of Nematode Infection: Virulence and Immunomodulatory Molecules From Nematode Parasites of Mammals, Insects and Plants.Frontiers in microbiology · 2020Review
- Advances in the Molecular and Cellular Biology ofCurrent tropical medicine reports · 2019Article
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Authors and funding
14 authors at 6 institutions in 1 country.
John B PattonDepartment of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, PA 19107.
Sandra Bonne-AnnéeDepartment of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, PA 19107.
Jessica DeckmanDepartment of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, PA 19107.
Jessica A HessDepartment of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, PA 19107.
April TorigianDepartment of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, PA 19107.
Thomas J NolanDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Zhu WangDepartment of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Steven A KliewerDepartment of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Amy C DurhamDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104.
James J LeeDivision of Pulmonary Medicine, Department of Biochemistry and Molecular Biology, Mayo Clinic, Scottsdale, AZ 85259.
Mark L EberhardDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA 30329.
David J MangelsdorfDepartment of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390; davo.mango@utsouthwestern.edu jlok@vet.upenn.edu david.abraham@jefferson.edu.ORCID 0000-0002-4355-0796
James B LokDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104; davo.mango@utsouthwestern.edu jlok@vet.upenn.edu david.abraham@jefferson.edu.
David AbrahamDepartment of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, PA 19107; davo.mango@utsouthwestern.edu jlok@vet.upenn.edu david.abraham@jefferson.edu.
Thomas Jefferson University · USUniversity of Pennsylvania · USHoward Hughes Medical Institute · USCenters for Disease Control and Prevention · USMayo Clinic in Arizona · USThe University of Texas Southwestern Medical Center · US
Funding
INSULIN-LIKE SIGNALING IN PARASITIC NEMATODE DEVELOPMENTR01AI050668 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HERBERT, DE'BROSKI R · 2002 to 2023
$7.1MTissue-specific Mechanism of Action of the Metabolic Hormones FGF19 and FGF21R01DK067158 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI KLIEWER, STEVEN A. · 2004 to 2017
$4.1MHUMAN STRONGYLOIDIASIS MODEL DEVELOPMENTR01AI022662 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI LOK, JAMES B · 1985 to 2012
$3.7MMechanisms and Treatment of Chronic, Latent Human StrongyloidiasisR33AI105856 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ABRAHAM, DAVID, LOK, JAMES B · 2015 to 2017
$1.4MMechanisms and Treatment of Chronic, Latent Human StrongyloidiasisR21AI105856 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ABRAHAM, DAVID, LOK, JAMES B · 2013 to 2014
$444kHoward Hughes Medical InstituteNIAID NIH HHS R01 AI022662NIAID NIH HHS R01 AI050668NIAID NIH HHS R21 AI105856NIAID NIH HHS R33 AI105856NIDDK NIH HHS R01 DK067158
Abstract
PubMed holds no abstract for this paper.
Indexed as
AnimalsCholestenesFemaleMethylprednisoloneMethylprednisolone AcetateMiceStrongyloides stercoralisStrongyloidiasisCholestenesdelta7-dafachronic acidMethylprednisoloneMethylprednisolone Acetatedafachronic acidglucocorticoidhyperinfectionNSG miceStrongyloides stercoralis
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.