Evidence map›Paper›PMID 29203652›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Divergence of regulatory networks governed by the orthologous transcription factors FLC and PEP1 in Brassicaceae species.

Julieta L Mateos, Vicky Tilmes, Pedro Madrigal, Edouard Severing, René Richter, Colin W M Rijkenberg, Paweł Krajewski, George Coupland

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
11.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
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  11. Evolutionary Dynamics ofPlants (Basel, Switzerland) · 2023
    Article
  12. Article
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  15. Article
  16. Article
  17. Article
  18. Review
  19. The Role ofFrontiers in plant science · 2020
    Review
  20. Gibberellins Act Downstream ofPlant physiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Julieta L MateosDepartment of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, D-50829 Cologne, Germany.ORCID 0000-0002-1156-6662
Vicky TilmesDepartment of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, D-50829 Cologne, Germany.
Pedro MadrigalDepartment of Biometry and Bioinformatics, Institute of Plant Genetics, Polish Academy of Sciences, 60-479 Poznań, Poland.ORCID 0000-0003-1959-8199
Edouard SeveringDepartment of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, D-50829 Cologne, Germany.
René RichterDepartment of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, D-50829 Cologne, Germany.
Colin W M RijkenbergDepartment of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, D-50829 Cologne, Germany.
Paweł KrajewskiDepartment of Biometry and Bioinformatics, Institute of Plant Genetics, Polish Academy of Sciences, 60-479 Poznań, Poland.
George CouplandDepartment of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, D-50829 Cologne, Germany; coupland@mpipz.mpg.de.
Max Planck Institute for Plant Breeding Research · DEInstitute of Plant Genetics, Polish Academy of Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome-wide landscapes of transcription factor (TF) binding sites (BSs) diverge during evolution, conferring species-specific transcriptional patterns. The rate of divergence varies in different metazoan lineages but has not been widely studied in plants. We identified the BSs and assessed the effects on transcription of FLOWERING LOCUS C (FLC) and PERPETUAL FLOWERING 1 (PEP1), two orthologous MADS-box TFs that repress flowering and confer vernalization requirement in the Brassicaceae species

Indexed as

Gene Expression Regulation, PlantGene Regulatory NetworksArabidopsis ProteinsBinding SitesBrassicaceaeEnvironmentFlowersGene-Environment InteractionGenetic VariationMADS Domain ProteinsNucleotide MotifsPlant ProteinsProtein BindingSequence Analysis, DNATranscription FactorsArabidopsis ProteinsAt5g10140 protein, ArabidopsisMADS Domain ProteinsPlant ProteinsTranscription FactorsArabidopsisArabis alpinabinding-site evolutionfloweringvernalization

Identifiers

PMID29203652
PMCPMC5754749
OpenAlexW2774636275

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.