ArticleProceedings of the National Academy of Sciences of the United States of America2017
Point-of-care device to diagnose and monitor neonatal jaundice in low-resource settings.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03866213 (Validation of a Low-Cost, Point-of-Care Bilirubin Measurement to Diagnose Neonatal Jaundice and Monitor Phototherapy in Hospitals in Sub-Saharan Africa), which is not on this map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Validation of a Low-Cost, Point-of-Care Bilirubin Measurement to Diagnose Neonatal Jaundice and Monitor Phototherapy in Hospitals in Sub-Saharan Africa
Who cites it
18 citing papers in PubMed, 74 citations in OpenAlex.
- Assessing Diagnostic Accuracy of a Handheld Point-of-Care Device for Quantifying Neonatal Bilirubin Levels: The BEAT Jaundice @Home Study.Neonatology · 2026Article
- Smartphone-integrated portable microfluidic platform for liver biomarker quantification using deep learning.Scientific reports · 2025Article
- Factors associated with neonatal jaundice among neonates admitted to three hospitals in Burao, Somaliland: a facility-based unmatched case-control study.BMC pediatrics · 2025Article
- Bilisense: An affordable sensor for on-site diagnosis of jaundice and prevention of kernicterus.Biosensors & bioelectronics · 2025Article
- A Method for Compensating Hemoglobin Interference in Total Serum Bilirubin Measurement Using a Simple Two-Wavelength Reflectance Photometer.Sensors (Basel, Switzerland) · 2024Article
- Validity of BiliDx as a point-of-care bilirubin measurement device to diagnose and monitor neonatal jaundice at Muhimbili National Hospital, an observational study.BMC pediatrics · 2024Observational
- Point-of-Care Testing for Hepatitis Viruses: A Growing Need.Life (Basel, Switzerland) · 2023Review
- Developing a novel device based on a new technology for non-invasive measurement of blood biomarkers irrespective of skin color.German medical science : GMS e-journal · 2023Observational
- Design and field evaluation of a lateral flow cassette device for point-of-care bilirubin measurement.PLOS global public health · 2023Article
- Management challenges in the treatment of severe hyperbilirubinemia in low- and middle-income countries: Encouraging advancements, remaining gaps, and future opportunities.Frontiers in pediatrics · 2023Review
- Development of a mobile phone camera-based transcutaneous bilirubinometer for low-resource settings.Biomedical optics express · 2022Article
- A review of existing neonatal hyperbilirubinemia guidelines in Indonesia.F1000Research · 2022Review
- A Low-Cost Paper-Based Device for the Colorimetric Quantification of Bilirubin in Serum Using Smartphone Technology.Frontiers in chemistry · 2022Article
- Diagnostic methods for neonatal hyperbilirubinemia: benefits, limitations, requirements, and novel developments.Pediatric research · 2021Review
- Review
- Catalytic hairpin assembly-assisted lateral flow assay for visual determination of microRNA-21 using gold nanoparticles.Mikrochimica acta · 2019Article
- Noninvasive transcutaneous bilirubin assessment of neonates with hyperbilirubinemia using a photon diffusion theory-based method.Biomedical optics express · 2019Article
- Laboratory validation and field usability assessment of a point-of-care test for serum bilirubin levels in neonates in a tropical setting.Wellcome open research · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Newborns are at increased risk of jaundice, a condition in which excess bilirubin accumulates in blood. Left untreated, jaundice can lead to neurological impairment and death. Jaundice resulting from unconjugated hyperbilirubinemia is easily treated with exposure to blue light, and phototherapy systems have been developed for low-resource settings; however, there are no appropriate solutions to diagnose and monitor jaundice in these settings. To address this need we present BiliSpec, a low-cost reader and disposable lateral flow card designed to measure the concentration of total bilirubin from several drops of blood at the point of care. We evaluated the performance of BiliSpec, using blood from normal volunteers spiked with varying amounts of bilirubin; results measured using BiliSpec correlated well with a reference laboratory bilirubinometer (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.