Evidence map›Paper›PMID 29203589›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2018

Lymph Node Metastases in Colon Cancer Are Polyclonal.

Peter J Ulintz, Joel K Greenson, Rong Wu, Eric R Fearon, Karin M Hardiman

Open access · greenAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Evolutionary paths towards metastasis.Nature reviews. Cancer · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Unusual Unique Renal Metastasis of Rectal Carcinoma.Journal of radiology case reports · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Anthelmintic Drugs as Emerging Immune Modulators in Cancer.International journal of molecular sciences · 2023
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Peter J UlintzBioinformatics Core, University of Michigan, Ann Arbor, Michigan.
Joel K GreensonDepartment of Pathology, University of Michigan, Ann Arbor, Michigan.
Rong WuDepartment of Pathology, University of Michigan, Ann Arbor, Michigan.
Eric R FearonDepartment of Pathology, University of Michigan, Ann Arbor, Michigan.
Karin M HardimanDepartment of Surgery, University of Michigan, Ann Arbor, Michigan. kmha@med.umich.edu.
University of Michigan–Ann Arbor · US

Funding

XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI THEODORE S LAWRENCE · 1988 to 2026
$178.2M
Translational Research in GI CancerP50CA130810 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BRENNER, DEAN E. · 2010 to 2016
$11.8M
CDX2 TUMOR SUPPRESSOR PATHWAY DEFECTS IN COLON CANCERR01CA082223 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FEARON, ERIC R. · 1999 to 2015
$3.9M
Intra-tumor Heterogeneity in Colorectal Cancer Progression and Treatment ResponseK08CA190645 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HARDIMAN, KARIN MARIE · 2016 to 2019
$700k
NCI NIH HHS K08 CA190645NCI NIH HHS L30 CA189003NCI NIH HHS P30 CA046592NCI NIH HHS P50 CA130810NCI NIH HHS R01 CA082223
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Clonal EvolutionAdultAgedChromosome MappingColorectal NeoplasmsComputational BiologyDNA Copy Number VariationsFemaleGene Expression ProfilingGenetic HeterogeneityHigh-Throughput Nucleotide SequencingHumansLymphatic MetastasisLymph NodesMaleMiddle Aged

Identifiers

PMID29203589
PMCPMC5932232
OpenAlexW2772813565

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.