Evidence map›Paper›PMID 29203527›Full record

ArticleThe Journal of biological chemistry2018

A novel chemical inducer of

Tiara G Pérez Morales, Kiira Ratia, Duo-Sheng Wang, Artemis Gogos, Laura Bloem, Tom G Driver, Michael J Federle

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Pathogens (Basel, Switzerland) · 2021
    Review
  5. AmBio · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Tiara G Pérez MoralesFrom the Center for Biomolecular Sciences, Department of Medicinal Chemistry and Pharmacognosy.
Kiira Ratiathe UIC High-throughput Screening Core Facility, and.
Duo-Sheng Wangthe Departments of Chemistry and.
Artemis GogosMicrobiology and Immunology, University of Illinois at Chicago, Chicago, Illinois 60607 and.
Laura BloemUICentre for Drug Discovery, University of Illinois at Chicago
Tom G Driverthe Departments of Chemistry and.
Michael J FederleFrom the Center for Biomolecular Sciences, Department of Medicinal Chemistry and Pharmacognosy, mfederle@uic.edu.ORCID 0000-0002-6322-1527
University of Illinois Chicago · USHuaqiao University · CNUniversity of Cologne · DE

Funding

Mechanistic Dissection of Pheromone-Dependent Regulation of Group A StreptococcalR01AI091779 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FEDERLE, MICHAEL J · 2011 to 2021
$3.9M
Molecular Mechanisms of Rgg Receptor Regulation by Pheromones and InhibitorsR01AI125452 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI FEDERLE, MICHAEL J, NEIDITCH, MATTHEW B · 2016 to 2019
$1.9M
NIAID NIH HHS R01 AI091779NIAID NIH HHS R01 AI125452
6 · The paper itself

Abstract

Bacteria produce chemical signals (pheromones) to coordinate behaviors across a population in a process termed quorum sensing (QS). QS systems comprising peptide pheromones and their corresponding Rgg receptors are widespread among

Indexed as

Bacterial ProteinsEndopeptidasesGene Expression Regulation, BacterialGram-Positive BacteriaNeprilysinPheromonesQuorum SensingSignal TransductionStreptococcus pyogenesBacterial ProteinsEndopeptidasesNeprilysinPheromonesantivirulencegene regulationgram-positive bacterianeprilysinpeptidasepheromonequorum quenchingquorum sensing

Identifiers

PMID29203527
PMCPMC5777264
OpenAlexW2772019018

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.