Evidence map›Paper›PMID 29203491›Full record

ArticleAntimicrobial agents and chemotherapy2018

Chemogenomic Profiling of the Fungal Pathogen Candida albicans.

Yaolin Chen, Jaideep Mallick, Alaa Maqnas, Yuan Sun, Baharul I Choudhury, Pierre Côte, Lan Yan, Ting-Jun-Hong Ni, Yan Li, Dazhi Zhang and 4 more

Erratum issuedAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. New hit compounds againstAntimicrobial agents and chemotherapy · 2026
    Article
  2. Article
  3. Review
  4. Antifungal Activity of Disalt of Epipyrone A fromJournal of fungi (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Article
  7. Application of the Mutant Libraries forInternational journal of molecular sciences · 2022
    Review
  8. Article
  9. Article
  10. The Role of Secretory Pathways inJournal of fungi (Basel, Switzerland) · 2020
    Review
  11. Article
  12. CRISPR-Based Genetic Manipulation ofFrontiers in genome editing · 2020
    Review
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Yaolin Chen *Biology Department, Concordia University, Montreal, Canada.
Jaideep Mallick *Biology Department, Concordia University, Montreal, Canada.
Alaa MaqnasBiology Department, Concordia University, Montreal, Canada.
Yuan SunBiology Department, Concordia University, Montreal, Canada.
Baharul I ChoudhuryBiology Department, Concordia University, Montreal, Canada.
Pierre CôteBiology Department, Concordia University, Montreal, Canada.
Lan YanCenter for New Drug Research, School of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China.
Ting-Jun-Hong NiDepartment of Organic Chemistry, School of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China.
Yan LiDepartment of Organic Chemistry, School of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China.
Dazhi ZhangDepartment of Organic Chemistry, School of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China.
Roberto Rodríguez-OrtizCONACYT, Institute of Neurobiology, UNAM, Juriquilla Campus, Querétaro, Mexico.
Quan-Zhen LvCenter for New Drug Research, School of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China.
Yuan-Ying JiangCenter for New Drug Research, School of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China.
Malcolm WhitewayBiology Department, Concordia University, Montreal, Canada malcolm.whiteway@concordia.ca.

Funding

CIHR MOP-42516
6 · The paper itself

Abstract

There is currently a small number of classes of antifungal drugs, and these drugs are known to target a very limited set of cellular functions. We derived a set of approximately 900 nonessential, transactivator-defective disruption strains from the tetracycline-regulated GRACE collection of strains of the fungal pathogen

Indexed as

Candida albicansdrug interactionsgenome analysis

Identifiers

PMID29203491
PMCPMC5786791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.