Evidence map›Paper›PMID 29203084›Full record

ArticlePatient education and counseling2018

The impact of genetic counselors' use of facilitative strategies on cognitive and emotional processing of genetic risk disclosure for Alzheimer's disease.

Yue Guan, Debra L Roter, Jennifer L Wolff, Laura N Gitlin, Kurt D Christensen, J Scott Roberts, Robert C Green, Lori H Erby

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Patient education and counseling, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01434667 (Risk Evaluation and Education for Alzheimer's Disease), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01434667 nacompletednot on this map

Risk Evaluation and Education for Alzheimer's Disease (REVEAL) IV

TypeinterventionalSponsorBrigham and Women's HospitalRan2010 to 2014Enrolled146ConditionsMild Cognitive ImpairmentArmsAPOE genotype and Alzheimer's disease risk disclosure, Alzheimer's disease risk disclosure
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yue GuanDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: yguan@som.umaryland.edu.
Debra L RoterDepartment of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Jennifer L WolffDepartment of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Laura N GitlinDepartment of Community Public Health, School of Nursing, Center for Innovative Care in Aging, Johns Hopkins University, Baltimore, MD, USA.
Kurt D ChristensenDivision of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
J Scott RobertsDepartment of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Robert C GreenDivision of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Partners Personalized Medicine, Boston, MA, USA.
Lori H ErbySocial and Behavioral Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
Neuropathology CoreP30AG013846 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI KOWALL, NEIL W. · 1996 to 2020
$29.1M
YOGA INDUCED CHANGES IN BRAIN GABA LEVELSM01RR000533 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HOLICK, MICHAEL F. · 1985 to 2008
$19.4M
UVDM01RR010284 · NCRR · HOWARD UNIVERSITY · PI TAYLOR, ROBERT E. · 1996 to 2010
$17.4M
Integration of Whole Genome Sequencing into Clinical MedicineU01HG006500 · NHGRI · BRIGHAM AND WOMEN'S HOSPITAL · PI GREEN, ROBERT C. · 2012 to 2016
$11.5M
Michigan Alzheimer's Disease Core CenterP30AG053760 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALBIN, ROGER L · 2016 to 2020
$10.1M
Risk Evaluation and Education for Alzheimer's Disease (REVEAL IV)R01HG002213 · NHGRI · BRIGHAM AND WOMEN'S HOSPITAL · PI GREEN, ROBERT C. · 1999 to 2012
$7.6M
Genome Sequence-Based Screening for Childhood Risk and Newborn IllnessU19HD077671 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI BEGGS, ALAN H., GREEN, ROBERT C. · 2013 to 2018
$6.1M
Cost-effectiveness of Whole Genome Sequencing of Healthy AdultsK01HG009173 · NHGRI · HARVARD PILGRIM HEALTH CARE, INC. · PI CHRISTENSEN, KURT DEREK · 2016 to 2020
$626k
NCATS NIH HHS UL1 TR001102NCRR NIH HHS M01 RR000533NCRR NIH HHS M01 RR010284NHGRI NIH HHS K01 HG009173NHGRI NIH HHS R01 HG002213NHGRI NIH HHS U01 HG006500NIA NIH HHS P30 AG013846NIA NIH HHS P30 AG053760NICHD NIH HHS U19 HD077671
6 · The paper itself

Abstract

objectivesTo determine the impact of genetic counselor (GC) communication on cognitive and emotional processing of Alzheimer's disease (AD) risk information during discussions with patients with clinical diagnoses of mild cognitive impairment and their companion.

methods79 recordings and transcripts of AD risk disclosure sessions collected as part of the fourth REVEAL Trial were coded using the Roter Interaction Analysis System (RIAS) and the Linguistic Inquiry Word Count (LIWC). Multilevel analyses were used to determine the association between GCs' use of communication facilitation strategies and patient and companion use of words indicative of cognitive and emotional processing.

resultsGC used somewhat more cognitive (14%) than emotional (10%) facilitation strategies. Both patients and companions used more words indicative of cognitive (18% and 17%) than emotional (6% and 5%) processing. GC use of facilitative strategies and patient and companion use of cognitive and emotional processing words were significantly associated in both unadjusted and adjusted models (all p-values<0.01).

conclusionsGCs' use of facilitative strategies assist in cognitive and emotional processing in a way that may be linked to therapeutic benefit. PRACTICE IMPLICATIONS: These findings highlight mechanisms through which GCs may assist patients and companions to better understand and cope with risk information.

Indexed as

CognitionCommunicationDisclosureEmotionsProfessional-Patient RelationsAdultAgedAged, 80 and overAlzheimer DiseaseCognitive DysfunctionCounselorsFamilyFemaleGenetic CounselingGenetic Predisposition to DiseaseHumansAlzheimer’s diseaseGenetic counselingGenetic testingPatient–provider communicationSocial cognitive processingVisit companion

Identifiers

PMID29203084
PMCPMC5911203

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.