Evidence map›Paper›PMID 29202893›Full record

Observational studyEpidemiology and infection2017

The role of the early social environment on Epstein Barr virus infection: a prospective observational design using the Millennium Cohort Study.

V Gares, L Panico, R Castagne, C Delpierre, M Kelly-Irving

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Epidemiology and infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.

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  19. Life Course Socioeconomic Disadvantage and the Aging Immune System: Findings From the Health and Retirement Study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

V GaresINSERM,UMR1027,F-31000 Toulouse,France.
L PanicoInstitut National d'Etudes Démographiques,75980 Paris cedex 20,France.
R CastagneINSERM,UMR1027,F-31000 Toulouse,France.
C DelpierreINSERM,UMR1027,F-31000 Toulouse,France.
M Kelly-IrvingINSERM,UMR1027,F-31000 Toulouse,France.
Inserm · FRUniversité Toulouse III - Paul Sabatier · FRInstitut national d'études démographiques · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epstein-Barr virus (EBV) is a highly prevalent herpesvirus linked to infectious mononucleosis and several malignancies. This paper aims to study the association between children's early life social environment at 9 months and EBV infection at 3 years of age.

methodsWe used data on children included in the UK Millennium Cohort Study. We described the social environment using area-level and material factors as well as socioeconomic position (SEP) at 9 months. EBV was measured at 3 years of age (n = 12 457).

resultsLower rates of EBV infection were observed in children living in towns and rural areas compared with those living in cities. Lower SEP and overcrowding in the household increased the odds of being infected. Children whose parents were social tenants were more likely to be infected than homeowners. In the overall model, the strength of the association between material factors and EBV infection weakened.

conclusionsWe showed that early life material deprivation was associated with a higher risk of EBV infection among 3-year-olds. Children living in more deprived social conditions may be more likely to become EBV carriers at an earlier age.

Indexed as

Social EnvironmentAdolescentAdultChildChild, PreschoolEpstein-Barr Virus InfectionsFemaleHerpesvirus 4, HumanHumansInfantInfant, NewbornMaleProspective StudiesRural PopulationSocioeconomic FactorsUnited KingdomEarly infectionsEpstein-Barr virusSocioeconomic inequalitiesUK

Identifiers

PMID29202893
PMCPMC9148726
OpenAlexW2772155099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.