Evidence map›Paper›PMID 29202822›Full record

ArticleBMC research notes2017

The p75

Alessandra de Perini, Ivan Dimauro, Guglielmo Duranti, Cristina Fantini, Neri Mercatelli, Roberta Ceci, Luigi Di Luigi, Stefania Sabatini, Daniela Caporossi

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Cell Surface Proteins for Enrichment andStem cells international · 2022
    Article
  6. Biological Aspects of Selected Myokines in Skeletal Muscle: Focus on Aging.International journal of molecular sciences · 2021
    Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Alessandra de PeriniDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis, 15, 00135, Rome, Italy.
Ivan DimauroDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis, 15, 00135, Rome, Italy.
Guglielmo DurantiDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis, 15, 00135, Rome, Italy.
Cristina FantiniDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis, 15, 00135, Rome, Italy.
Neri MercatelliDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis, 15, 00135, Rome, Italy.
Roberta CeciDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis, 15, 00135, Rome, Italy.
Luigi Di LuigiDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis, 15, 00135, Rome, Italy.
Stefania SabatiniDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis, 15, 00135, Rome, Italy.
Daniela CaporossiDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis, 15, 00135, Rome, Italy. daniela.caporossi@uniroma4.it.ORCID http://orcid.org/0000-0001-9628-0665
Foro Italico University of Rome · IT

Funding

Foro Italico University Research Grant 2015
6 · The paper itself

Abstract

objectiveDuring muscle development or regeneration, myocytes produce nerve growth factor (NGF) as well as its tyrosine-kinase and p75-neurotrophin (p75

resultsAlthough NGF was not effective in modulating myogenic cell growth or survival in both standard or stress conditions, we demonstrated for the first time that, under serum deprivation, NGF sustained the activity of some key enzymes involved in energy metabolism. Moreover, we confirmed that NGF promotes myogenic fusion and expression of the structural protein myosin heavy chain while modulating NFκB activation and the content of sHSPs correlated with the differentiation process. We conclude that p75

Indexed as

3-Hydroxyacyl-CoA DehydrogenaseAnimalsCell CycleCell DifferentiationCell FusionCell LineCitrate (si)-SynthaseCrystallinsCulture Media, Serum-FreeEnergy MetabolismGene Expression RegulationHSP27 Heat-Shock ProteinsL-Lactate DehydrogenaseMicrotubule-Associated ProteinsMuscle DevelopmentMuscle Fibers, Skeletal3-Hydroxyacyl-CoA DehydrogenaseCitrate (si)-SynthasecryaB protein, ratCrystallinsCulture Media, Serum-FreeHSP27 Heat-Shock ProteinsHspb1 protein, ratL-Lactate DehydrogenaseMicrotubule-Associated ProteinsMyosin Heavy ChainsNerve Growth FactorNerve Tissue ProteinsNF-kappa BNgfr protein, ratReceptors, Growth FactorReceptors, Nerve Growth FactorEnergy metabolismMyogenic differentiationNFκBNGFp75NTRsHSPs

Identifiers

PMID29202822
PMCPMC5716223
OpenAlexW2773718239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.