ArticleBMC nephrology2017
Prevalence and determinants of differences in cystatin C and creatinine-based estimated glomerular filtration rate in community-dwelling older adults: a cross-sectional study.
Article in BMC nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- The Difference Between Cystatin C- and Creatinine-Based Estimated GFR and Associations With Frailty and Adverse Outcomes: A Cohort Analysis of the Systolic Blood Pressure Intervention Trial (SPRINT).American journal of kidney diseases : the official journal of the National Kidney Foundation · 2020Trial
- Discrepancy between cystatin C-based and creatinine-based eGFR predicts all-cause mortality in a community-based population: the Takahata study.Clinical and experimental nephrology · 2026Article
- Difference between estimated glomerular filtration rate based on cystatin c versus creatinine and risk of hypertension: a prospective cohort study.European journal of medical research · 2025Article
- Association of Intraindividual Difference in Cystatin C and Creatinine Estimated Glomerular Filtration Rate With Diabetes.Journal of diabetes research · 2025Article
- Large Discordance between Creatinine-Based and Cystatin C-Based eGFRs is Associated with Falls, Hospitalizations, and Death in Older Adults.Clinical journal of the American Society of Nephrology : CJASN · 2024Article
- Article
- Chronic kidney disease and its association with cerebral small vessel disease in the general older hypertensive population.BMC nephrology · 2024Article
- Estimated GFR Accuracy When Cystatin C- and Creatinine-Based Estimates Are Discrepant in Older Adults.Kidney medicine · 2023Article
- Association of Intra-individual Differences in Estimated GFR by Creatinine Versus Cystatin C With Incident Heart Failure.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2022Article
- Comparison of Creatinine and Cystatin C to Estimate Renal Function in Geriatric and Frail Patients.Life (Basel, Switzerland) · 2022Article
- Association of Intraindividual Difference in Estimated Glomerular Filtration Rate by Creatinine vs Cystatin C and End-stage Kidney Disease and Mortality.JAMA network open · 2022Observational
- Utility of a Score for Predicting Glomerular Filtration Rate Overestimation in Patients with Cardiovascular and Renal Diseases and Their Risk Factors.Internal medicine (Tokyo, Japan) · 2022Article
- Processing speed is affected by early impairment in kidney function in the general elder population.BMC nephrology · 2021Article
- Assessment of kidney function: clinical indications for measured GFR.Clinical kidney journal · 2021Review
- Kidney Function Is Not Related to Brain Amyloid Burden on PET Imaging in The 90+ Study Cohort.Frontiers in medicine · 2021Article
- Cystatin C may be better than creatinine for digoxin dosing in older adults with atrial fibrillation.Journal of clinical laboratory analysis · 2020Article
- Impaired kidney function is associated with lower cognitive function in the elder general population. Results from the Good Aging in Skåne (GÅS) cohort study.BMC geriatrics · 2019Article
- Cystatin C and creatinine-based eGFR levels and their correlation to long-term morbidity and mortality in older adults.Aging clinical and experimental research · 2019Article
- Obesity and recovery from acute kidney injury (Ob AKI): a prospective cohort feasibility study.BMJ open · 2019Article
- Differences in Kidney Function Estimates Based on Creatinine and/or Cystatin C in Non-Traumatic Amputation Patients and Their Impact on Drug Prescribing.Journal of clinical medicine · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDifferences in cystatin C and creatinine-based estimated glomerular filtration rate (eGFR) can lead to clinical uncertainty. Existing eGFR equations perform poorly in a subset of individuals. This study aims to describe the prevalence of differences between cystatin C-based (eGFR
methodsIn this cross-sectional study, participants from a cohort of community-dwelling older adults were examined at a baseline visit in 2001-2004 as part of the larger "Good Aging in Skåne" study. Exposure variables were obtained from questionnaires, interviews, examinations, and medical records. Blood samples were taken during the baseline visit, cryopreserved, and analyzed at a later time for biomarkers. The CKD-EPI equations were used to estimate GFR. Initial descriptive analyses were performed on 2931 individuals. A total of 2532 participants were included in the final multiple linear regression.
resultsNearly two-thirds of participants had eGFR differences exceeding 10%, with nearly 20 % of participants having eGFR differences exceeding 30%. Smoking, age, body mass index (BMI), C-reactive protein (CRP), glucocorticoid use, and mean eGFR were correlated with differences between eGFR
conclusionsDifferences between eGFR
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