Evidence map›Paper›PMID 29202803›Full record

ReviewGenome medicine2017

Emerging mechanisms and novel targets in allergic inflammation and asthma.

Scott T Weiss

Open access · goldAbstract readReview
In one paragraph

Review in Genome medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Scott T WeissHarvard Medical School and Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA. scott.weiss@channing.harvard.edu.
Harvard University · US

Funding

The Genetic Epidemiology of Asthma in Costa RicaR37HL066289 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISS, SCOTT T · 2007 to 2015
$14.6M
Systems Biology of Airway DiseaseP01HL132825 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DEMEO, DAWN L · 2016 to 2020
$12.6M
Physics of collective cellular migration in lung health and diseaseP01HL120839 · NHLBI · HARVARD SCHOOL OF PUBLIC HEALTH · PI FREDBERG, JEFFREY J · 2014 to 2018
$12.2M
Randomized Trial: Maternal Vitamin D Supplementation to Prevent Childhood AsthmaU01HL091528 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LITONJUA, AUGUSTO A, WEISS, SCOTT T · 2009 to 2013
$10.0M
RANDOMIZED CONTROLLED TRIAL: VDAART CONTINUATION STUDY - DCC - LEADR01HL091528 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LITONJUA, AUGUSTO A, WEISS, SCOTT T · 2014 to 2018
$9.1M
THE GENETIC EPIDEMIOLOGY OF ASTHMA IN COSTA RICAR01HL066289 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISS, SCOTT T · 2001 to 2005
$5.2M
Multi-omic approaches to mechanisms of vitamin D, environmental influences, and the microbiome on asthmaUG3OD023268 · OD · BRIGHAM AND WOMEN'S HOSPITAL · PI LITONJUA, AUGUSTO A, WEISS, SCOTT T · 2016 to 2017
$2.8M
NHLBI NIH HHS P01 HL120839NHLBI NIH HHS P01 HL132825NHLBI NIH HHS R01 HL066289NHLBI NIH HHS R01 HL091528NHLBI NIH HHS R37 HL066289NHLBI NIH HHS U01 HL091528NIH HHS UG3 OD023268
6 · The paper itself

Abstract

Airway inflammation is key to the severity and persistence of asthma. Recent studies have revealed novel immune mechanisms that target dendritic cells, T helper 2 cytokines, regulatory T cells, and type 2 innate lymphoid cells in allergic inflammation, as well as novel approaches that target airway smooth muscle in asthma. These advances inform the development of new targeted treatments for allergic inflammation and asthma with the potential to provide therapeutic benefit.

Indexed as

AnimalsAntibodies, MonoclonalAnti-Inflammatory AgentsAsthmaHumansImmunologic FactorsImmunotherapyAntibodies, MonoclonalAnti-Inflammatory AgentsImmunologic Factors

Identifiers

PMID29202803
PMCPMC5713157
OpenAlexW2771865481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.