Evidence map›Paper›PMID 29202751›Full record

Trial reportNutrition journal2017

Walnut consumption in a weight reduction intervention: effects on body weight, biological measures, blood pressure and satiety.

Cheryl L Rock, Shirley W Flatt, Hava-Shoshana Barkai, Bilge Pakiz, Dennis D Heath

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrition journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02501889 (Walnut Consumption in a Weight Loss Intervention), which is not on this map. Cited by 38 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 8 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02501889 nacompletednot on this map

Walnut Consumption in a Weight Loss Intervention: Effects on Weight Change, Satiety and Potential Mediating Factors

TypeinterventionalSponsorUniversity of California, San DiegoRan2015 to 2017Enrolled100ConditionsOverweight and ObesityArmsWalnut-rich weight loss diet, Standard weight loss diet
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 8 syntheses or guidelines pooled it, 74 citations in OpenAlex.

  1. Effects of Walnut (Juglans regia L.) on Blood Pressure and Endothelial Function in Adults: A Systematic Review and Dose-Response Meta-Analysis.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
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  18. Neuroprotective and antimalarial effects ofFrontiers in veterinary science · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cheryl L RockDepartment of Family Medicine and Public Health, School of Medicine, University of California, 3855 Health Sciences Drive, Room 3077, La Jolla, CA, 92093-0901, USA. clrock@ucsd.edu.ORCID http://orcid.org/0000-0002-6661-7391
Shirley W FlattDepartment of Family Medicine and Public Health, School of Medicine, University of California, 3855 Health Sciences Drive, Room 3077, La Jolla, CA, 92093-0901, USA.
Hava-Shoshana BarkaiDepartment of Family Medicine and Public Health, School of Medicine, University of California, 3855 Health Sciences Drive, Room 3077, La Jolla, CA, 92093-0901, USA.
Bilge PakizDepartment of Family Medicine and Public Health, School of Medicine, University of California, 3855 Health Sciences Drive, Room 3077, La Jolla, CA, 92093-0901, USA.
Dennis D HeathDepartment of Family Medicine and Public Health, School of Medicine, University of California, 3855 Health Sciences Drive, Room 3077, La Jolla, CA, 92093-0901, USA.
University of California San Diego · US

Funding

American Institute for Cancer Research n/aCalifornia Walnut Commission n/a
6 · The paper itself

Abstract

backgroundDietary strategies that help patients adhere to a weight reduction diet may increase the likelihood of weight loss maintenance and improved long-term health outcomes. Regular nut consumption has been associated with better weight management and less adiposity. The objective of this study was to compare the effects of a walnut-enriched reduced-energy diet to a standard reduced-energy-density diet on weight, cardiovascular disease risk factors, and satiety.

methodsOverweight and obese men and women (n = 100) were randomly assigned to a standard reduced-energy-density diet or a walnut-enriched (15% of energy) reduced-energy diet in the context of a behavioral weight loss intervention. Measurements were obtained at baseline and 3- and 6-month clinic visits. Participants rated hunger, fullness and anticipated prospective consumption at 3 time points during the intervention. Body measurements, blood pressure, physical activity, lipids, tocopherols and fatty acids were analyzed using repeated measures mixed models.

resultsBoth study groups reduced body weight, body mass index and waist circumference (time effect p < 0.001 for each). Change in weight was -9.4 (0.9)% vs. -8.9 (0.7)% (mean [SE]), for the standard vs. walnut-enriched diet groups, respectively. Systolic blood pressure decreased in both groups at 3 months, but only the walnut-enriched diet group maintained a lower systolic blood pressure at 6 months. The walnut-enriched diet group, but not the standard reduced-energy-density diet group, reduced total cholesterol and low-density lipoprotein cholesterol (LDL-C) at 6 months, from 203 to 194 mg/dL and 121 to 112 mg/dL, respectively (p < 0.05). Self-reported satiety was similar in the groups.

conclusionsThese findings provide further evidence that a walnut-enriched reduced-energy diet can promote weight loss that is comparable to a standard reduced-energy-density diet in the context of a behavioral weight loss intervention. Although weight loss in response to both dietary strategies was associated with improvements in cardiovascular disease risk factors, the walnut-enriched diet promoted more favorable effects on LDL-C and systolic blood pressure.

trial registrationThe trial is registered at ( NCT02501889 ).

Indexed as

Blood PressureJuglansNutsSatiationWeight LossBehavior TherapyBody Mass IndexBody WeightCholesterol, LDLDiet, ReducingEnergy IntakeFemaleHumansMaleMiddle AgedObesityCholesterol, LDLBlood pressureCardiovascular disease risk factorsNutsSatietyWeight loss

Identifiers

PMID29202751
PMCPMC5715655
OpenAlexW2773870795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.