Evidence map›Paper›PMID 29202747›Full record

ArticleBMC public health2017

Seroprevalence of toxoplasmosis and risk factors of Toxoplasma gondii infection among pregnant women in Sri Lanka: a cross sectional study.

Devika Iddawela, Sanura Malinda Pallegoda Vithana, Chathura Ratnayake

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
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  15. International journal of environmental research and public health · 2021
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  17. Seroepidemiology ofInfection and drug resistance · 2021
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  18. Risk factors forEpidemiology and infection · 2020
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  19. Seroprevalence and risk factors associated withParasite epidemiology and control · 2020
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Devika IddawelaDepartment of Parasitology, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
Sanura Malinda Pallegoda VithanaDepartment of Parasitology, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka. san_mp01@hotmail.com.
Chathura RatnayakeDepartment of Obstetrics and Gynaecology, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
University of Peradeniya · LK

Funding

National Research Council, Sri Lanka. Grant No.07-37.
6 · The paper itself

Abstract

backgroundToxoplasma gondii is an intracellular protozoan infecting humans and animals. Infection in adults usually causes mild disease but greater importance lies in preventing transplacental transmission which can cause major foetal anomalies and is vital to identify infection in pregnancy. Research on this regard in Sri Lanka is scarce and would be beneficial in developing antenatal care strategies for improved foetal outcome.

methodsA random sample of 536 pregnant women attending antenatal care in Teaching Hospital Peradeniya from 2010 to 2013 was recruited for this study. Blood samples were tested for Toxoplasma gondii IgG and IgM antibodies from the participants by using a commercial ELISA kit with a cut-off OD value of >1 and a structured questionnaire was used to identify the exposure to risk. Bivariate analysis using the Chi Square test was used to calculate associations between documented risk factors and seropositivity and a p value of <0.05 was taken as significant.

resultsAmong the participants 160 (29.9%) were positive for T. gondii IgG antibodies and 2 (0.37%) were IgM positive. The seroprevalence in the first, second and third trimesters were 30.4%, 30.6% and 26.1% respectively. Of the risk factors studied, preparation and selling raw meat (p = 0.05) and household gardening (p = 0.01) were significant whereas the presence of domesticated cats and dogs, eating locally produced meat or dairy products did not show significant associations.

conclusionsSeroprevalence of T. gondii present among pregnant women attending antenatal care in Peradeniya was 29.9% indicating high level of transmission among the study population. However 70.1% of the study population were seronegative and were susceptible to primary acute infection during pregnancy and possible foetal anomalies. Therefore implementing health education especially on the aforementioned risk factors is recommended.

Indexed as

AdolescentAdultAntibodies, ProtozoanCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayFemaleHospitals, TeachingHumansImmunoglobulin GImmunoglobulin MMiddle AgedPregnancyPregnancy Complications, ParasiticPrenatal CareRisk FactorsSeroepidemiologic StudiesAntibodies, ProtozoanImmunoglobulin GImmunoglobulin MSri LankaToxoplasma gondiiToxoplasmosis

Identifiers

PMID29202747
PMCPMC5716377
OpenAlexW2774036540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.